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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 27.27
Human Site: Y974 Identified Species: 46.15
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 Y974 P K S V E G Y Y Q E S G R A G
Chimpanzee Pan troglodytes XP_510594 1417 158822 Y974 P K S M E G Y Y Q E S G R A G
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 Y973 P K S M E G Y Y Q E S G R A G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 Y982 P K S M E G Y Y Q E S G R A G
Rat Rattus norvegicus Q6AYJ1 621 69624 I194 I Y V T P E K I A K S K M F M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186 H364 C L L F Y S Y H D V I R L K R
Chicken Gallus gallus Q9I920 1142 126164 E715 G R A G R D G E M S H C L L F
Frog Xenopus laevis Q9DEY9 1364 152305 Y926 P K S V E G Y Y Q E S G R A G
Zebra Danio Brachydanio rerio XP_701357 1261 139417 N834 E L R R M F P N V P I M A L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 Y1043 P K S I E G Y Y Q E A G R A G
Honey Bee Apis mellifera XP_396209 961 109321 G534 A H C V S Q W G H D F R P D Y
Nematode Worm Caenorhab. elegans O18017 988 110641 G561 Y Q E T G R A G R D G M P S Y
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 I959 T P R V K T D I L H A L K M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 Y985 P R T L E G Y Y Q E T G R A G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 93.3 93.3 N.A. N.A. 93.3 6.6 N.A. 6.6 0 100 0 N.A. 86.6 6.6 0 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 13.3 N.A. 13.3 13.3 100 0 N.A. 100 20 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 8 0 8 0 15 0 8 50 0 % A
% Cys: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 0 8 15 0 0 0 8 0 % D
% Glu: 8 0 8 0 50 8 0 8 0 50 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 8 0 0 0 0 8 0 0 8 8 % F
% Gly: 8 0 0 8 8 50 8 15 0 0 8 50 0 0 50 % G
% His: 0 8 0 0 0 0 0 8 8 8 8 0 0 0 0 % H
% Ile: 8 0 0 8 0 0 0 15 0 0 15 0 0 0 0 % I
% Lys: 0 43 0 0 8 0 8 0 0 8 0 8 8 8 8 % K
% Leu: 0 15 8 8 0 0 0 0 8 0 0 8 15 15 0 % L
% Met: 0 0 0 22 8 0 0 0 8 0 0 15 8 8 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 50 8 0 0 8 0 8 0 0 8 0 0 15 0 0 % P
% Gln: 0 8 0 0 0 8 0 0 50 0 0 0 0 0 0 % Q
% Arg: 0 15 15 8 8 8 0 0 8 0 0 15 50 0 8 % R
% Ser: 0 0 43 0 8 8 0 0 0 8 43 0 0 8 0 % S
% Thr: 8 0 8 15 0 8 0 0 0 0 8 0 0 0 8 % T
% Val: 0 0 8 29 0 0 0 0 8 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 8 0 58 50 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _