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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIRA All Species: 33.33
Human Site: S382 Identified Species: 45.83
UniProt: P54198 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54198 NP_003316.3 1017 111835 S382 H Q S T Y G K S L A I M T E A
Chimpanzee Pan troglodytes XP_001165585 1017 111787 S382 H Q S T Y G K S L A I M T E A
Rhesus Macaque Macaca mulatta XP_001112873 1138 124408 L503 Q S T Y G K S L A I M T E A Q
Dog Lupus familis XP_543550 1017 111618 S382 H Q S T Y G K S L A I M T E A
Cat Felis silvestris
Mouse Mus musculus Q61666 1015 111748 S382 H Q S T Y G K S L A I M T E A
Rat Rattus norvegicus NP_001129232 1015 111665 S382 H Q S T Y G K S L A I M T E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P79987 1019 112055 S382 H Q S T Y G K S L A I M T E A
Frog Xenopus laevis Q8QFR2 1013 112021 S382 H Q S T Y G K S L A I T T E P
Zebra Danio Brachydanio rerio XP_696478 1010 111223 S382 H Q N I Y G K S L A I T M E S
Tiger Blowfish Takifugu rubipres O42611 1025 111838 S382 H Q N I Y G K S L A I T N T E
Fruit Fly Dros. melanogaster O17468 1047 113397 N379 I R K M Y G K N Y V N G L G K
Honey Bee Apis mellifera XP_001122939 838 91355 P228 V L R L S W S P D G Q Y L V S
Nematode Worm Caenorhab. elegans Q09589 935 103412 I325 P L F V I N N I F N H T V M D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q32SG6 964 105548 A354 P D G Y S L F A C S L D G S A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXN4 1051 115544 V382 K K S R Y G D V R G R Q A N L
Baker's Yeast Sacchar. cerevisiae P32479 840 93871 P230 T E P F K E S P L T T Y F R R
Red Bread Mold Neurospora crassa Q7RZI0 1035 112420 W380 F E T G E L G W V A K S E E N
Conservation
Percent
Protein Identity: 100 99.9 88.4 96.5 N.A. 95.7 95.5 N.A. N.A. 86 78 69.8 67.7 31.1 40 26.5 N.A.
Protein Similarity: 100 99.9 88.9 98 N.A. 97.5 97.7 N.A. N.A. 93.1 88.5 83.2 81.3 48 55.1 46.1 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. N.A. 100 86.6 66.6 60 20 0 0 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. N.A. 100 86.6 80 66.6 33.3 6.6 0 N.A.
Percent
Protein Identity: N.A. 25.6 N.A. 25 22.4 25.9
Protein Similarity: N.A. 43.7 N.A. 43.3 41.2 45.8
P-Site Identity: N.A. 6.6 N.A. 20 6.6 13.3
P-Site Similarity: N.A. 26.6 N.A. 26.6 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 6 6 59 0 0 6 6 42 % A
% Cys: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 0 0 6 0 6 0 0 6 0 0 6 % D
% Glu: 0 12 0 0 6 6 0 0 0 0 0 0 12 53 6 % E
% Phe: 6 0 6 6 0 0 6 0 6 0 0 0 6 0 0 % F
% Gly: 0 0 6 6 6 65 6 0 0 12 0 6 6 6 0 % G
% His: 53 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % H
% Ile: 6 0 0 12 6 0 0 6 0 6 53 0 0 0 0 % I
% Lys: 6 6 6 0 6 6 59 0 0 0 6 0 0 0 6 % K
% Leu: 0 12 0 6 0 12 0 6 59 0 6 0 12 0 6 % L
% Met: 0 0 0 6 0 0 0 0 0 0 6 36 6 6 0 % M
% Asn: 0 0 12 0 0 6 6 6 0 6 6 0 6 6 6 % N
% Pro: 12 0 6 0 0 0 0 12 0 0 0 0 0 0 6 % P
% Gln: 6 53 0 0 0 0 0 0 0 0 6 6 0 0 6 % Q
% Arg: 0 6 6 6 0 0 0 0 6 0 6 0 0 6 6 % R
% Ser: 0 6 48 0 12 0 18 53 0 6 0 6 0 6 12 % S
% Thr: 6 0 12 42 0 0 0 0 0 6 6 30 42 6 0 % T
% Val: 6 0 0 6 0 0 0 6 6 6 0 0 6 6 0 % V
% Trp: 0 0 0 0 0 6 0 6 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 65 0 0 0 6 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _