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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
13.94
Human Site:
S498
Identified Species:
19.17
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S498
T
M
L
S
S
H
S
S
P
Q
L
L
P
L
D
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S498
T
M
L
S
S
H
S
S
P
Q
L
L
P
L
D
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S619
T
M
L
S
S
H
S
S
P
Q
L
L
P
L
D
Dog
Lupus familis
XP_543550
1017
111618
N498
T
M
L
S
S
H
S
N
P
Q
L
L
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
G498
T
M
L
S
S
P
S
G
Q
Q
L
L
P
L
D
Rat
Rattus norvegicus
NP_001129232
1015
111665
G498
T
M
L
S
S
P
S
G
Q
Q
L
L
P
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S498
T
L
A
G
S
I
M
S
S
Q
N
N
Q
Q
L
Frog
Xenopus laevis
Q8QFR2
1013
112021
N498
S
M
M
S
S
Q
S
N
Q
Q
L
I
S
L
D
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
I498
S
T
Q
L
T
P
Q
I
S
S
D
S
N
T
A
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
T498
S
S
M
S
N
Q
L
T
S
Q
L
S
S
D
S
Fruit Fly
Dros. melanogaster
O17468
1047
113397
L495
P
L
M
P
L
E
P
L
V
S
K
I
D
L
G
Honey Bee
Apis mellifera
XP_001122939
838
91355
S344
A
A
C
S
W
D
G
S
V
V
L
I
E
F
T
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
E441
I
Q
L
T
K
S
M
E
D
N
S
K
E
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
K470
P
T
A
D
D
V
K
K
G
N
Q
L
S
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
G498
E
N
N
I
M
I
N
G
E
S
H
N
F
L
P
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
R346
V
W
S
T
S
R
P
R
P
I
L
V
A
F
D
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
K496
V
T
I
T
K
D
G
K
K
R
V
A
P
L
L
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
26.6
53.3
0
20
6.6
20
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
N.A.
33.3
80
13.3
46.6
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
6.6
26.6
13.3
P-Site Similarity:
N.A.
6.6
N.A.
13.3
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
12
0
0
0
0
0
0
0
0
6
6
0
6
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
6
12
0
0
6
0
6
0
6
6
48
% D
% Glu:
6
0
0
0
0
6
0
6
6
0
0
0
12
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
6
12
0
% F
% Gly:
0
0
0
6
0
0
12
18
6
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
24
0
0
0
0
6
0
0
0
0
% H
% Ile:
6
0
6
6
0
12
0
6
0
6
0
18
0
0
0
% I
% Lys:
0
0
0
0
12
0
6
12
6
0
6
6
0
0
0
% K
% Leu:
0
12
42
6
6
0
6
6
0
0
59
42
0
59
12
% L
% Met:
0
42
18
0
6
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
6
0
6
0
6
12
0
12
6
12
6
6
0
% N
% Pro:
12
0
0
6
0
18
12
0
30
0
0
0
42
0
12
% P
% Gln:
0
6
6
0
0
12
6
0
18
53
6
0
6
6
0
% Q
% Arg:
0
0
0
0
0
6
0
6
0
6
0
0
0
0
0
% R
% Ser:
18
6
6
53
53
6
42
30
18
18
6
12
18
6
6
% S
% Thr:
42
18
0
18
6
0
0
6
0
0
0
0
0
6
6
% T
% Val:
12
0
0
0
0
6
0
0
12
6
6
6
0
0
0
% V
% Trp:
0
6
0
0
6
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _