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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
15.15
Human Site:
S573
Identified Species:
20.83
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S573
D
S
R
F
T
E
R
S
K
A
T
P
G
A
P
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S573
D
S
R
F
T
E
R
S
K
A
T
P
G
A
P
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S694
D
S
R
F
T
E
R
S
K
A
T
P
G
A
P
Dog
Lupus familis
XP_543550
1017
111618
S573
D
S
R
F
T
E
R
S
K
A
T
P
G
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
K573
S
R
F
T
E
R
S
K
A
T
P
G
A
P
S
Rat
Rattus norvegicus
NP_001129232
1015
111665
K573
S
R
F
T
E
R
S
K
A
T
P
G
A
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S573
E
P
M
K
A
F
D
S
R
F
T
E
R
S
K
Frog
Xenopus laevis
Q8QFR2
1013
112021
A573
R
F
T
E
R
S
K
A
T
S
G
T
A
G
V
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
V573
R
S
K
A
T
P
G
V
T
S
V
P
I
T
I
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
G573
E
R
S
K
A
T
P
G
A
T
A
A
I
A
S
Fruit Fly
Dros. melanogaster
O17468
1047
113397
V570
A
L
D
Y
R
L
H
V
S
N
G
H
L
K
T
Honey Bee
Apis mellifera
XP_001122939
838
91355
P419
P
T
T
T
A
T
T
P
A
K
G
P
I
N
K
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
K516
A
P
A
V
P
A
K
K
G
E
V
D
L
E
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
R545
N
N
C
G
V
K
D
R
T
S
V
T
A
R
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
V573
G
R
D
G
V
L
N
V
E
Q
S
V
G
I
K
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
Q421
D
F
P
E
S
I
N
Q
L
L
L
E
D
Q
T
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
E571
I
V
E
D
E
E
E
E
E
P
S
A
K
R
S
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
N.A.
13.3
0
20
6.6
0
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
0
0
N.A.
N.A.
33.3
20
33.3
13.3
6.6
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
26.6
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
6
6
18
6
0
6
24
24
6
12
24
30
6
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
12
6
0
0
12
0
0
0
0
6
6
0
6
% D
% Glu:
12
0
6
12
18
30
6
6
12
6
0
12
0
6
0
% E
% Phe:
0
12
12
24
0
6
0
0
0
6
0
0
0
0
0
% F
% Gly:
6
0
0
12
0
0
6
6
6
0
18
12
30
6
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% H
% Ile:
6
0
0
0
0
6
0
0
0
0
0
0
18
6
6
% I
% Lys:
0
0
6
12
0
6
12
18
24
6
0
0
6
6
18
% K
% Leu:
0
6
0
0
0
12
0
0
6
6
6
0
12
0
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
0
0
0
0
12
0
0
6
0
0
0
6
0
% N
% Pro:
6
12
6
0
6
6
6
6
0
6
12
36
0
12
24
% P
% Gln:
0
0
0
0
0
0
0
6
0
6
0
0
0
6
0
% Q
% Arg:
12
24
24
0
12
12
24
6
6
0
0
0
6
12
0
% R
% Ser:
12
30
6
0
6
6
12
30
6
18
12
0
0
6
24
% S
% Thr:
0
6
12
18
30
12
6
0
18
18
30
12
0
6
12
% T
% Val:
0
6
0
6
12
0
0
18
0
0
18
6
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _