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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIRA All Species: 38.18
Human Site: S698 Identified Species: 52.5
UniProt: P54198 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54198 NP_003316.3 1017 111835 S698 A F T L Q V S S D P S M Y I E
Chimpanzee Pan troglodytes XP_001165585 1017 111787 S698 A F T L Q V S S D P S M Y I E
Rhesus Macaque Macaca mulatta XP_001112873 1138 124408 S819 A F T L Q V S S D P S M Y I E
Dog Lupus familis XP_543550 1017 111618 S698 A F T L Q V S S D P S M Y I E
Cat Felis silvestris
Mouse Mus musculus Q61666 1015 111748 S696 A F T L Q V S S D P S M Y I E
Rat Rattus norvegicus NP_001129232 1015 111665 S696 A F T L Q V S S D P S M Y I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P79987 1019 112055 S704 S F T L Q V S S D P S M Y L E
Frog Xenopus laevis Q8QFR2 1013 112021 S694 S F T L Q L S S D P S M Y I E
Zebra Danio Brachydanio rerio XP_696478 1010 111223 T691 S F S T Q V G T D A V T Y L E
Tiger Blowfish Takifugu rubipres O42611 1025 111838 M706 A F T L Q V S M D P S V V L E
Fruit Fly Dros. melanogaster O17468 1047 113397 S716 N S Y S Y S T S L Q S W L V L
Honey Bee Apis mellifera XP_001122939 838 91355 L537 N Q I I L P P L K P S S S L S
Nematode Worm Caenorhab. elegans Q09589 935 103412 T634 L I K K K Q Q T A E N E D D M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q32SG6 964 105548 W663 L A G N A N F W A V G C E D G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXN4 1051 115544 L719 L F N R K C V L H D S L S S L
Baker's Yeast Sacchar. cerevisiae P32479 840 93871 T539 K T I N S K N T L L N V P E G
Red Bread Mold Neurospora crassa Q7RZI0 1035 112420 I697 D F L P R A I I L V A G S K H
Conservation
Percent
Protein Identity: 100 99.9 88.4 96.5 N.A. 95.7 95.5 N.A. N.A. 86 78 69.8 67.7 31.1 40 26.5 N.A.
Protein Similarity: 100 99.9 88.9 98 N.A. 97.5 97.7 N.A. N.A. 93.1 88.5 83.2 81.3 48 55.1 46.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 86.6 40 73.3 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 66.6 86.6 26.6 26.6 20 N.A.
Percent
Protein Identity: N.A. 25.6 N.A. 25 22.4 25.9
Protein Similarity: N.A. 43.7 N.A. 43.3 41.2 45.8
P-Site Identity: N.A. 0 N.A. 13.3 0 6.6
P-Site Similarity: N.A. 0 N.A. 26.6 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 6 0 0 6 6 0 0 12 6 6 0 0 0 0 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 0 6 0 0 0 % C
% Asp: 6 0 0 0 0 0 0 0 59 6 0 0 6 12 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 6 0 6 6 6 59 % E
% Phe: 0 71 0 0 0 0 6 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 6 0 0 0 6 0 0 0 6 6 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 6 % H
% Ile: 0 6 12 6 0 0 6 6 0 0 0 0 0 42 0 % I
% Lys: 6 0 6 6 12 6 0 0 6 0 0 0 0 6 0 % K
% Leu: 18 0 6 53 6 6 0 12 18 6 0 6 6 24 12 % L
% Met: 0 0 0 0 0 0 0 6 0 0 0 48 0 0 6 % M
% Asn: 12 0 6 12 0 6 6 0 0 0 12 0 0 0 0 % N
% Pro: 0 0 0 6 0 6 6 0 0 59 0 0 6 0 0 % P
% Gln: 0 6 0 0 59 6 6 0 0 6 0 0 0 0 0 % Q
% Arg: 0 0 0 6 6 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 18 6 6 6 6 6 53 53 0 0 71 6 18 6 6 % S
% Thr: 0 6 53 6 0 0 6 18 0 0 0 6 0 0 0 % T
% Val: 0 0 0 0 0 53 6 0 0 12 6 12 6 6 0 % V
% Trp: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 0 % W
% Tyr: 0 0 6 0 6 0 0 0 0 0 0 0 53 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _