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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
35.45
Human Site:
T462
Identified Species:
48.75
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
T583
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Dog
Lupus familis
XP_543550
1017
111618
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Rat
Rattus norvegicus
NP_001129232
1015
111665
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
R462
E
T
R
T
A
D
G
R
R
R
I
T
P
L
C
Frog
Xenopus laevis
Q8QFR2
1013
112021
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
T462
A
D
G
R
R
R
I
T
P
L
C
I
A
Q
L
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
R462
R
T
P
D
G
R
R
R
I
T
P
L
C
I
A
Fruit Fly
Dros. melanogaster
O17468
1047
113397
S459
S
M
N
I
V
S
S
S
G
S
S
T
T
A
L
Honey Bee
Apis mellifera
XP_001122939
838
91355
S308
S
L
S
V
W
L
T
S
L
K
R
P
L
V
V
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
S405
N
L
S
D
L
S
S
S
A
N
N
A
S
F
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
S434
G
K
A
P
P
K
V
S
A
G
V
P
N
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
V462
K
A
S
T
L
N
R
V
S
S
P
V
N
Q
K
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
V310
D
D
P
E
N
A
L
V
G
Q
N
D
D
K
V
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
G460
G
K
A
A
D
T
N
G
T
T
T
P
A
P
P
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
100
100
6.6
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
100
100
13.3
20
20
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
20
N.A.
13.3
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
48
6
12
6
6
6
0
0
12
0
0
6
53
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
48
0
6
0
6
% C
% Asp:
6
53
0
12
6
6
0
0
0
0
0
6
6
0
0
% D
% Glu:
6
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% F
% Gly:
12
0
48
0
6
0
6
6
12
6
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
0
48
0
6
0
6
48
0
6
0
% I
% Lys:
6
12
0
0
0
6
0
0
0
6
0
0
0
6
6
% K
% Leu:
0
12
0
0
12
6
6
0
6
48
0
6
6
6
53
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
6
0
6
6
6
0
0
6
12
0
12
0
0
% N
% Pro:
0
0
12
6
6
0
0
0
48
0
12
18
6
12
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
6
0
0
0
53
0
% Q
% Arg:
6
0
6
48
48
53
12
12
6
6
6
0
0
0
0
% R
% Ser:
12
0
18
0
0
12
12
24
6
12
6
0
6
0
0
% S
% Thr:
0
12
0
12
0
6
6
48
6
12
6
12
6
0
0
% T
% Val:
0
0
0
6
6
0
6
12
0
0
6
6
0
6
18
% V
% Trp:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _