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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
36.36
Human Site:
T735
Identified Species:
50
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T735
K
E
W
E
T
V
L
T
S
R
I
L
T
A
A
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T735
K
E
W
E
T
V
L
T
S
R
I
L
T
A
A
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
T856
K
E
W
E
T
V
L
T
S
R
I
L
T
A
A
Dog
Lupus familis
XP_543550
1017
111618
T735
K
E
W
E
T
V
L
T
S
R
I
L
T
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S733
K
E
W
E
T
V
L
S
S
R
V
L
T
A
A
Rat
Rattus norvegicus
NP_001129232
1015
111665
S733
K
E
W
E
T
V
L
S
S
R
V
L
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T741
K
E
W
E
T
V
L
T
S
R
I
L
T
A
A
Frog
Xenopus laevis
Q8QFR2
1013
112021
T731
K
E
W
E
A
V
L
T
S
R
I
V
A
A
A
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
P728
R
E
W
D
T
L
L
P
S
R
I
I
I
A
T
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
P743
R
D
W
N
T
L
L
P
S
S
V
L
T
A
A
Fruit Fly
Dros. melanogaster
O17468
1047
113397
S753
Q
Q
K
F
P
L
L
S
M
Q
A
S
S
Q
N
Honey Bee
Apis mellifera
XP_001122939
838
91355
T574
K
G
T
D
S
E
P
T
W
D
L
Y
L
G
Y
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
N671
I
V
A
A
N
K
H
N
V
V
L
G
C
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
S700
V
F
I
D
C
D
D
S
W
K
L
L
L
V
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
V756
I
F
L
V
G
D
L
V
V
E
L
L
S
W
Y
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
W576
G
T
K
E
R
S
A
W
K
I
S
N
S
E
L
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
Q734
N
A
I
M
L
E
S
Q
P
V
I
L
E
A
R
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
100
80
53.3
53.3
6.6
13.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
86.6
80
80
46.6
33.3
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
13.3
6.6
20
P-Site Similarity:
N.A.
33.3
N.A.
26.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
6
6
0
6
0
0
0
6
0
6
65
53
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
0
6
0
18
0
12
6
0
0
6
0
0
0
0
6
% D
% Glu:
0
53
0
53
0
12
0
0
0
6
0
0
6
6
0
% E
% Phe:
0
12
0
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
6
0
0
6
0
0
0
0
0
0
6
0
12
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
0
0
0
0
0
0
6
48
6
6
0
0
% I
% Lys:
53
0
12
0
0
6
0
0
6
6
0
0
0
0
0
% K
% Leu:
0
0
6
0
6
18
71
0
0
0
24
65
12
0
6
% L
% Met:
0
0
0
6
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
6
0
0
6
6
0
0
6
0
0
0
6
0
0
6
% N
% Pro:
0
0
0
0
6
0
6
12
6
0
0
0
0
0
0
% P
% Gln:
6
6
0
0
0
0
0
6
0
6
0
0
0
6
0
% Q
% Arg:
12
0
0
0
6
0
0
0
0
53
0
0
0
0
6
% R
% Ser:
0
0
0
0
6
6
6
24
59
6
6
6
18
0
0
% S
% Thr:
0
6
6
0
53
0
0
42
0
0
0
0
48
0
12
% T
% Val:
6
6
0
6
0
48
0
6
12
12
18
6
0
6
0
% V
% Trp:
0
0
59
0
0
0
0
6
12
0
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _