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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
38.48
Human Site:
Y703
Identified Species:
52.92
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
Y703
V
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
Y703
V
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
Y824
V
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Dog
Lupus familis
XP_543550
1017
111618
Y703
V
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
Y701
V
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Rat
Rattus norvegicus
NP_001129232
1015
111665
Y701
V
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
Y709
V
S
S
D
P
S
M
Y
L
E
V
E
N
E
M
Frog
Xenopus laevis
Q8QFR2
1013
112021
Y699
L
S
S
D
P
S
M
Y
I
E
V
E
N
E
V
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
Y696
V
G
T
D
A
V
T
Y
L
E
V
E
N
E
V
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
V711
V
S
M
D
P
S
V
V
L
E
V
E
N
E
V
Fruit Fly
Dros. melanogaster
O17468
1047
113397
L721
S
T
S
L
Q
S
W
L
V
L
A
T
K
D
A
Honey Bee
Apis mellifera
XP_001122939
838
91355
S542
P
P
L
K
P
S
S
S
L
S
Q
Q
A
G
H
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
D639
Q
Q
T
A
E
N
E
D
D
M
M
D
G
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
E668
N
F
W
A
V
G
C
E
D
G
F
L
Q
V
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
S724
C
V
L
H
D
S
L
S
S
L
V
S
S
D
V
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
P544
K
N
T
L
L
N
V
P
E
G
V
E
K
K
I
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
S702
A
I
I
L
V
A
G
S
K
H
F
W
A
A
A
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
60
73.3
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
73.3
86.6
33.3
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
20
13.3
0
P-Site Similarity:
N.A.
0
N.A.
40
53.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
12
6
6
0
0
0
0
6
0
12
6
12
% A
% Cys:
6
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
59
6
0
0
6
12
0
0
6
0
12
0
% D
% Glu:
0
0
0
0
6
0
6
6
6
59
0
65
0
65
0
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
6
0
0
0
6
6
0
0
12
0
0
6
6
0
% G
% His:
0
0
0
6
0
0
0
0
0
6
0
0
0
0
6
% H
% Ile:
0
6
6
0
0
0
0
0
42
0
0
0
0
0
6
% I
% Lys:
6
0
0
6
0
0
0
0
6
0
0
0
12
6
0
% K
% Leu:
6
0
12
18
6
0
6
6
24
12
0
6
0
0
0
% L
% Met:
0
0
6
0
0
0
48
0
0
6
6
0
0
0
6
% M
% Asn:
6
6
0
0
0
12
0
0
0
0
0
0
59
0
0
% N
% Pro:
6
6
0
0
59
0
0
6
0
0
0
0
0
0
0
% P
% Gln:
6
6
0
0
6
0
0
0
0
0
6
6
6
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% R
% Ser:
6
53
53
0
0
71
6
18
6
6
0
6
6
0
0
% S
% Thr:
0
6
18
0
0
0
6
0
0
0
0
6
0
0
0
% T
% Val:
53
6
0
0
12
6
12
6
6
0
71
0
0
6
59
% V
% Trp:
0
0
6
0
0
0
6
0
0
0
0
6
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
53
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _