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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC18A1
All Species:
21.82
Human Site:
S492
Identified Species:
40
UniProt:
P54219
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54219
NP_001129163.1
525
56257
S492
E
E
K
L
A
I
L
S
Q
D
C
P
M
E
T
Chimpanzee
Pan troglodytes
XP_001150127
525
56327
S492
E
E
K
L
A
I
L
S
Q
D
C
P
M
E
T
Rhesus Macaque
Macaca mulatta
XP_001100696
525
56229
S492
E
E
K
L
A
I
L
S
Q
D
C
P
M
E
T
Dog
Lupus familis
XP_543264
524
56658
S491
K
E
N
L
A
I
L
S
E
D
S
V
M
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R090
521
56015
N489
E
E
E
L
A
I
L
N
Q
E
C
P
T
E
T
Rat
Rattus norvegicus
Q01818
521
55917
S489
E
E
K
R
A
I
L
S
Q
E
C
P
T
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512181
547
59642
I515
A
K
E
E
K
M
A
I
L
M
D
H
N
C
S
Chicken
Gallus gallus
XP_428881
522
55697
S489
E
E
K
I
A
I
L
S
Q
E
G
P
M
Q
T
Frog
Xenopus laevis
NP_001079414
471
51040
I439
W
L
M
V
I
L
G
I
I
N
L
A
Y
A
P
Zebra Danio
Brachydanio rerio
P59845
493
53034
R461
D
S
I
R
L
E
E
R
A
L
R
R
K
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O17444
578
64295
E498
Q
Q
Y
Q
Q
E
Q
E
T
N
L
D
D
Q
Q
Honey Bee
Apis mellifera
XP_392061
522
56234
L490
Y
A
P
L
M
Y
F
L
R
A
P
P
T
K
E
Nematode Worm
Caenorhab. elegans
P34711
532
58625
Y499
G
W
E
D
Q
Q
S
Y
Q
N
Q
A
Q
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.3
85.1
N.A.
82.2
82.8
N.A.
63.6
72
51
36.1
N.A.
30.9
54
32.3
N.A.
Protein Similarity:
100
99.6
97.7
90.6
N.A.
89.3
88.7
N.A.
77.6
82.4
66.8
55.4
N.A.
51.5
70.6
54.3
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
73.3
80
N.A.
0
73.3
0
0
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
86.6
N.A.
26.6
93.3
20
6.6
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
54
0
8
0
8
8
0
16
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
39
0
0
8
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
31
8
8
8
0
0
% D
% Glu:
47
54
24
8
0
16
8
8
8
24
0
0
0
47
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
8
8
54
0
16
8
0
0
0
0
8
0
% I
% Lys:
8
8
39
0
8
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
8
0
47
8
8
54
8
8
8
16
0
0
0
8
% L
% Met:
0
0
8
0
8
8
0
0
0
8
0
0
39
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
24
0
0
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
8
54
0
0
16
% P
% Gln:
8
8
0
8
16
8
8
0
54
0
8
0
8
16
8
% Q
% Arg:
0
0
0
16
0
0
0
8
8
0
8
8
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
47
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
24
0
54
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _