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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC18A1
All Species:
34.55
Human Site:
Y219
Identified Species:
63.33
UniProt:
P54219
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54219
NP_001129163.1
525
56257
Y219
L
G
M
L
A
S
V
Y
T
D
D
H
E
R
G
Chimpanzee
Pan troglodytes
XP_001150127
525
56327
Y219
L
G
M
L
A
S
V
Y
T
D
D
H
E
R
G
Rhesus Macaque
Macaca mulatta
XP_001100696
525
56229
Y219
L
G
M
L
A
S
V
Y
T
D
D
H
E
R
G
Dog
Lupus familis
XP_543264
524
56658
Y218
L
G
M
L
A
S
V
Y
T
D
D
Y
E
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R090
521
56015
Y216
L
G
M
L
A
S
V
Y
T
D
N
Y
E
R
G
Rat
Rattus norvegicus
Q01818
521
55917
Y216
L
G
M
L
A
S
V
Y
T
D
N
Y
E
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512181
547
59642
Y244
M
G
M
L
A
S
I
Y
T
D
D
E
E
R
G
Chicken
Gallus gallus
XP_428881
522
55697
Y216
L
G
M
L
A
S
I
Y
T
D
D
F
E
R
G
Frog
Xenopus laevis
NP_001079414
471
51040
D195
L
A
H
V
F
P
D
D
T
E
R
G
K
A
M
Zebra Danio
Brachydanio rerio
P59845
493
53034
G217
A
C
V
C
L
A
D
G
V
L
L
L
T
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O17444
578
64295
M231
V
C
L
L
D
G
L
M
L
L
L
V
M
K
P
Honey Bee
Apis mellifera
XP_392061
522
56234
Y232
M
G
M
L
A
E
R
Y
Q
D
D
K
E
R
G
Nematode Worm
Caenorhab. elegans
P34711
532
58625
A236
V
C
L
A
D
A
I
A
V
F
M
V
I
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.3
85.1
N.A.
82.2
82.8
N.A.
63.6
72
51
36.1
N.A.
30.9
54
32.3
N.A.
Protein Similarity:
100
99.6
97.7
90.6
N.A.
89.3
88.7
N.A.
77.6
82.4
66.8
55.4
N.A.
51.5
70.6
54.3
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
86.6
13.3
0
N.A.
6.6
66.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
33.3
13.3
N.A.
33.3
73.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
70
16
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
24
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
16
8
0
70
54
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
8
0
8
70
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
70
0
0
0
8
0
8
0
0
0
8
0
0
70
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
24
0
0
0
% H
% Ile:
0
0
0
0
0
0
24
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% K
% Leu:
62
0
16
77
8
0
8
0
8
16
16
8
0
0
0
% L
% Met:
16
0
70
0
0
0
0
8
0
0
8
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
8
0
0
70
0
% R
% Ser:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
70
0
0
0
8
0
0
% T
% Val:
16
0
8
8
0
0
47
0
16
0
0
16
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _