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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATXN3 All Species: 30.91
Human Site: T122 Identified Species: 52.31
UniProt: P54252 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54252 NP_001121168.1 364 41781 T122 N Y K E H W F T V R K L G K Q
Chimpanzee Pan troglodytes XP_001146724 368 42242 T122 N Y K E H W F T V R K L G K Q
Rhesus Macaque Macaca mulatta XP_001116022 352 40079 A141 L I S D T Y L A L F L A Q L Q
Dog Lupus familis XP_537352 301 34778 Y116 E R S F I C N Y K E H W F T V
Cat Felis silvestris
Mouse Mus musculus Q9CVD2 355 40515 T122 N Y K E H W F T V R K L G K Q
Rat Rattus norvegicus O35815 355 40428 T122 N Y K E H W F T V R K L G K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507271 358 40934 T122 N Y K E H W F T V R K L G K Q
Chicken Gallus gallus Q9W689 363 41590 T122 N Y K E H W F T V R K L G K Q
Frog Xenopus laevis NP_001085659 316 35907 L118 L A L F L A Q L Q Q E G Y S I
Zebra Danio Brachydanio rerio NP_957398 266 30028 L81 H W F T V R K L G Q Q W F N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623341 340 38556 T124 N Y K G H W F T I R K I G K Q
Nematode Worm Caenorhab. elegans O17850 317 35845 V120 N L R E H W F V L R K F G N Q
Sea Urchin Strong. purpuratus XP_786733 388 42119 T148 N F R E H W L T I R K L G N Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M391 280 30674 D95 Q K A L E V W D L Q V I P L N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 88.7 79.1 N.A. 80.2 80.4 N.A. 78 70.5 52.2 50.5 N.A. N.A. 42.8 31.3 38.4
Protein Similarity: 100 97.8 90.1 80.7 N.A. 85.4 85.7 N.A. 85.1 79.9 64.8 61.8 N.A. N.A. 59.6 48.6 56.4
P-Site Identity: 100 100 6.6 0 N.A. 100 100 N.A. 100 100 0 0 N.A. N.A. 80 60 66.6
P-Site Similarity: 100 100 26.6 0 N.A. 100 100 N.A. 100 100 13.3 26.6 N.A. N.A. 93.3 73.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 29.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 0 8 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 58 8 0 0 0 0 8 8 0 0 0 0 % E
% Phe: 0 8 8 15 0 0 58 0 0 8 0 8 15 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 8 0 0 8 65 0 0 % G
% His: 8 0 0 0 65 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 0 15 0 0 15 0 0 8 % I
% Lys: 0 8 50 0 0 0 8 0 8 0 65 0 0 50 0 % K
% Leu: 15 8 8 8 8 0 15 15 22 0 8 50 0 15 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 65 0 0 0 0 0 8 0 0 0 0 0 0 22 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 8 22 8 0 8 0 72 % Q
% Arg: 0 8 15 0 0 8 0 0 0 65 0 0 0 0 0 % R
% Ser: 0 0 15 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 8 8 0 0 58 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 8 8 0 8 43 0 8 0 0 0 8 % V
% Trp: 0 8 0 0 0 65 8 0 0 0 0 15 0 0 0 % W
% Tyr: 0 50 0 0 0 8 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _