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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
20.3
Human Site:
S288
Identified Species:
40.61
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S288
N
L
K
C
L
K
E
S
T
R
L
Y
P
V
F
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S417
N
L
K
C
L
K
E
S
T
R
L
Y
P
V
F
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
C243
L
S
G
F
L
P
K
C
D
A
D
H
S
F
T
Dog
Lupus familis
XP_536002
930
105612
A288
N
L
K
C
L
K
E
A
S
R
L
Y
P
I
F
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
S267
S
G
R
H
K
T
F
S
T
F
R
A
S
F
H
Rat
Rattus norvegicus
NP_001009535
919
103710
S288
N
L
K
C
L
K
E
S
T
R
L
Y
P
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
Y279
I
L
K
V
I
R
Q
Y
C
G
R
R
G
Q
K
Chicken
Gallus gallus
NP_001006508
916
103017
S284
S
V
L
M
Q
K
D
S
T
R
L
Y
P
V
F
Frog
Xenopus laevis
NP_001079545
925
103654
S288
T
Q
S
L
N
K
G
S
P
R
C
Y
P
V
F
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
Y279
I
L
K
L
I
K
Q
Y
Y
T
S
A
Q
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
S146
T
G
T
T
V
T
A
S
R
L
F
H
N
I
P
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
N290
N
E
L
Y
K
G
A
N
S
R
Q
Y
P
I
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
6.6
80
N.A.
13.3
93.3
N.A.
13.3
60
46.6
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
26.6
100
N.A.
33.3
80
46.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
9
0
9
0
17
0
0
9
% A
% Cys:
0
0
0
34
0
0
0
9
9
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
34
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
9
0
0
9
9
0
0
17
50
% F
% Gly:
0
17
9
0
0
9
9
0
0
9
0
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
17
0
0
9
% H
% Ile:
17
0
0
0
17
0
0
0
0
0
0
0
0
34
0
% I
% Lys:
0
0
50
0
17
59
9
0
0
0
0
0
0
0
9
% K
% Leu:
9
50
17
17
42
0
0
0
0
9
42
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
0
0
0
9
0
0
9
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
9
0
0
0
59
0
9
% P
% Gln:
0
9
0
0
9
0
17
0
0
0
9
0
9
9
0
% Q
% Arg:
0
0
9
0
0
9
0
0
9
59
17
9
0
0
0
% R
% Ser:
17
9
9
0
0
0
0
59
17
0
9
0
17
9
0
% S
% Thr:
17
0
9
9
0
17
0
0
42
9
0
0
0
0
9
% T
% Val:
0
9
0
9
9
0
0
0
0
0
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
17
9
0
0
59
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _