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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
14.55
Human Site:
S646
Identified Species:
29.09
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S646
I
E
Q
E
S
Q
M
S
L
K
D
G
R
K
K
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S775
I
E
Q
E
S
Q
M
S
L
K
D
G
R
K
K
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
S597
L
I
E
N
P
K
T
S
L
E
D
A
T
L
Q
Dog
Lupus familis
XP_536002
930
105612
S646
I
E
Q
E
S
Q
I
S
L
K
D
G
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
S621
L
L
E
F
S
L
S
S
L
A
K
R
M
K
Q
Rat
Rattus norvegicus
NP_001009535
919
103710
K642
S
L
K
D
G
R
K
K
L
R
A
T
G
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
T633
G
R
R
V
D
G
S
T
S
L
T
D
P
R
L
Chicken
Gallus gallus
NP_001006508
916
103017
P638
M
Q
Q
A
A
R
R
P
V
K
E
N
E
R
Q
Frog
Xenopus laevis
NP_001079545
925
103654
K642
E
K
Q
K
D
S
E
K
R
Q
K
M
S
S
R
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
L634
N
Q
Q
A
L
D
K
L
F
S
S
Q
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
I500
L
T
E
P
S
G
K
I
V
Q
P
S
V
L
L
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
F657
S
R
L
Q
S
G
K
F
T
F
G
G
S
K
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
20
93.3
N.A.
26.6
6.6
N.A.
0
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
53.3
100
N.A.
46.6
33.3
N.A.
20
66.6
33.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
0
0
0
0
9
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
17
9
0
0
0
0
34
9
0
0
0
% D
% Glu:
9
25
25
25
0
0
9
0
0
9
9
0
9
0
0
% E
% Phe:
0
0
0
9
0
0
0
9
9
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
25
0
0
0
0
9
34
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
9
0
9
34
17
0
34
17
0
0
42
25
% K
% Leu:
25
17
9
0
9
9
0
9
50
9
0
0
0
17
17
% L
% Met:
9
0
0
0
0
0
17
0
0
0
0
9
9
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
9
9
0
0
9
0
0
9
0
17
0
0
% P
% Gln:
0
17
50
9
0
25
0
0
0
17
0
9
0
0
25
% Q
% Arg:
0
17
9
0
0
17
9
0
9
9
0
9
25
17
17
% R
% Ser:
17
0
0
0
50
9
17
42
9
9
9
9
17
17
9
% S
% Thr:
0
9
0
0
0
0
9
9
9
0
9
9
9
0
0
% T
% Val:
0
0
0
9
0
0
0
0
17
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _