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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
27.88
Human Site:
T311
Identified Species:
55.76
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
T311
A
D
V
D
V
N
L
T
P
D
K
S
Q
V
L
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
T440
A
D
V
D
V
N
L
T
P
D
K
S
Q
V
L
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
P266
F
I
F
I
N
S
R
P
V
H
Q
K
D
I
L
Dog
Lupus familis
XP_536002
930
105612
T311
A
D
V
D
V
N
I
T
P
D
K
S
Q
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
S290
V
Q
Q
T
G
S
F
S
S
S
I
R
G
P
V
Rat
Rattus norvegicus
NP_001009535
919
103710
T311
A
E
V
D
I
N
L
T
P
D
K
S
Q
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
P302
F
F
V
N
I
V
V
P
T
A
S
V
D
V
N
Chicken
Gallus gallus
NP_001006508
916
103017
T307
S
A
V
D
V
N
V
T
P
D
K
T
E
V
L
Frog
Xenopus laevis
NP_001079545
925
103654
T311
S
C
L
D
V
N
L
T
P
D
K
T
K
I
M
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
T302
P
T
F
M
M
N
I
T
I
P
A
S
T
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
L169
A
K
R
R
R
D
E
L
K
K
V
E
D
L
L
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
T313
T
A
C
D
V
N
V
T
P
D
K
R
K
I
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
6.6
93.3
N.A.
0
86.6
N.A.
13.3
66.6
53.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
20
100
N.A.
33.3
93.3
93.3
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
17
0
0
0
0
0
0
0
9
9
0
0
0
0
% A
% Cys:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
59
0
9
0
0
0
59
0
0
25
0
9
% D
% Glu:
0
9
0
0
0
0
9
0
0
0
0
9
9
0
0
% E
% Phe:
17
9
17
0
0
0
9
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
9
17
0
17
0
9
0
9
0
0
25
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
9
59
9
17
0
0
% K
% Leu:
0
0
9
0
0
0
34
9
0
0
0
0
0
9
59
% L
% Met:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
9
67
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
17
59
9
0
0
0
9
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
9
0
34
0
0
% Q
% Arg:
0
0
9
9
9
0
9
0
0
0
0
17
0
0
0
% R
% Ser:
17
0
0
0
0
17
0
9
9
9
9
42
0
0
0
% S
% Thr:
9
9
0
9
0
0
0
67
9
0
0
17
9
0
0
% T
% Val:
9
0
50
0
50
9
25
0
9
0
9
9
0
59
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _