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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
16.97
Human Site:
Y902
Identified Species:
33.94
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
Y902
E
D
I
Q
D
I
I
Y
R
M
K
H
Q
F
G
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
Y1031
E
D
I
Q
D
I
I
Y
R
M
K
H
Q
F
G
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
I811
K
H
Q
F
G
N
E
I
K
G
C
V
H
G
R
Dog
Lupus familis
XP_536002
930
105612
Y900
E
D
V
Q
D
I
I
Y
R
M
K
D
Q
F
G
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
N839
G
E
M
D
H
P
W
N
C
P
H
G
R
P
T
Rat
Rattus norvegicus
NP_001009535
919
103710
Y889
E
D
V
Q
D
L
I
Y
K
M
K
H
Q
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
H847
V
P
A
G
P
V
T
H
P
R
P
E
R
M
S
Chicken
Gallus gallus
NP_001006508
916
103017
Y884
E
D
V
E
N
T
I
Y
R
M
K
Q
Q
L
G
Frog
Xenopus laevis
NP_001079545
925
103654
H892
E
D
V
Q
D
I
M
H
R
V
K
N
Q
L
G
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
C855
A
D
V
T
N
T
L
C
R
M
Q
Q
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
W675
N
K
I
L
Q
R
Q
W
A
E
L
N
E
E
E
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
E877
N
E
M
Q
K
I
L
E
H
L
V
D
L
K
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
0
86.6
N.A.
0
80
N.A.
0
60
60
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
20
100
N.A.
20
80
93.3
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
9
0
9
0
0
0
0
% C
% Asp:
0
59
0
9
42
0
0
0
0
0
0
17
0
0
0
% D
% Glu:
50
17
0
9
0
0
9
9
0
9
0
9
17
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
34
0
% F
% Gly:
9
0
0
9
9
0
0
0
0
9
0
9
0
9
50
% G
% His:
0
9
0
0
9
0
0
17
9
0
9
25
9
0
0
% H
% Ile:
0
0
25
0
0
42
42
9
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
9
0
0
0
17
0
50
0
0
9
0
% K
% Leu:
0
0
0
9
0
9
17
0
0
9
9
0
9
25
0
% L
% Met:
0
0
17
0
0
0
9
0
0
50
0
0
0
9
0
% M
% Asn:
17
0
0
0
17
9
0
9
0
0
0
17
0
0
0
% N
% Pro:
0
9
0
0
9
9
0
0
9
9
9
0
0
9
0
% P
% Gln:
0
0
9
50
9
0
9
0
0
0
9
17
50
0
9
% Q
% Arg:
0
0
0
0
0
9
0
0
50
9
0
0
17
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% S
% Thr:
0
0
0
9
0
17
9
0
0
0
0
0
0
0
9
% T
% Val:
9
0
42
0
0
9
0
0
0
9
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _