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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
10
Human Site:
S6
Identified Species:
22
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
S6
_
_
M
E
R
A
E
S
S
S
T
E
P
A
K
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
S6
_
_
M
E
R
A
E
S
S
S
T
E
P
A
K
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
Dog
Lupus familis
XP_536879
876
97273
V16
A
L
F
L
V
T
D
V
F
S
T
E
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
G6
_
_
M
E
Q
T
E
G
V
S
T
E
C
A
K
Rat
Rattus norvegicus
P97679
757
84522
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
S8
S
Y
I
E
R
P
D
S
S
S
L
E
P
A
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
I12
C
I
E
S
A
G
A
I
K
A
I
D
K
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
V7
_
M
A
V
A
G
K
V
K
A
I
D
R
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
S8
M
Q
G
D
S
S
P
S
P
T
T
T
S
S
P
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
I10
Q
I
H
Q
I
N
D
I
D
V
H
R
I
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
100
0
33.3
N.A.
61.5
0
N.A.
60
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
40
N.A.
69.2
0
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
21.4
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
19
19
10
0
0
19
0
0
0
46
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
0
0
28
0
10
0
0
19
0
0
0
% D
% Glu:
0
0
10
37
0
0
28
0
0
0
0
46
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
19
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
19
10
0
10
0
0
19
0
0
19
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
19
0
0
0
10
0
46
% K
% Leu:
0
10
0
10
0
0
0
0
0
0
10
0
10
0
0
% L
% Met:
10
10
28
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
10
0
0
0
28
0
10
% P
% Gln:
10
10
0
10
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
28
0
0
0
0
0
0
10
10
10
0
% R
% Ser:
10
0
0
10
10
10
0
37
28
46
0
0
10
10
28
% S
% Thr:
0
0
0
0
0
19
0
0
0
10
46
10
0
10
0
% T
% Val:
0
0
0
10
10
0
0
19
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
37
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% _