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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA2D1
All Species:
17.27
Human Site:
S23
Identified Species:
47.5
UniProt:
P54289
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54289
NP_000713.2
1103
124568
S23
S
L
L
I
G
P
S
S
E
E
P
F
P
S
A
Chimpanzee
Pan troglodytes
XP_001160235
1110
125290
S23
S
L
L
I
G
P
S
S
E
E
P
F
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001090735
1453
162781
S363
L
L
A
A
P
G
A
S
A
Y
S
F
P
Q
Q
Dog
Lupus familis
XP_852918
1147
129632
D79
T
F
G
C
Q
R
S
D
G
T
F
S
S
D
F
Cat
Felis silvestris
Mouse
Mus musculus
O08532
1103
124612
S23
S
G
L
I
G
P
S
S
E
E
P
F
P
S
P
Rat
Rattus norvegicus
P54290
1091
123805
S23
S
W
L
I
G
P
S
S
E
E
P
F
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506420
1113
125732
A45
N
S
V
V
L
N
S
A
K
S
S
A
Q
Y
S
Chicken
Gallus gallus
NP_001170793
1082
122672
S23
S
L
V
M
N
H
S
S
E
G
P
F
P
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34374
1249
144358
N21
V
S
T
T
S
S
F
N
K
E
S
I
K
E
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
43.4
90.2
N.A.
96.4
93.7
N.A.
84.9
79.3
N.A.
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
100
99.1
55.1
91.8
N.A.
98.6
96
N.A.
90.7
88.1
N.A.
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
100
100
26.6
6.6
N.A.
86.6
86.6
N.A.
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
13.3
N.A.
86.6
86.6
N.A.
46.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
12
12
12
0
0
12
0
0
23
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
56
56
0
0
0
12
0
% E
% Phe:
0
12
0
0
0
0
12
0
0
0
12
67
0
0
12
% F
% Gly:
0
12
12
0
45
12
0
0
12
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
45
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
23
0
0
0
12
0
0
% K
% Leu:
12
45
45
0
12
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
12
12
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
45
0
0
0
0
56
0
67
0
34
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
12
12
12
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% R
% Ser:
56
23
0
0
12
12
78
67
0
12
34
12
12
56
12
% S
% Thr:
12
0
12
12
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
12
0
23
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _