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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YARS All Species: 40.91
Human Site: S312 Identified Species: 64.29
UniProt: P54577 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54577 NP_003671.1 528 59143 S312 H P G D L K N S V E V A L N K
Chimpanzee Pan troglodytes XP_524651 528 59111 S312 H P G D L K N S V E V A L N K
Rhesus Macaque Macaca mulatta XP_001104797 526 58788 S310 H P G D L K N S V E V A L N K
Dog Lupus familis XP_535324 511 57292 S295 H P G D L K N S V E V A L N K
Cat Felis silvestris
Mouse Mus musculus Q91WQ3 528 59087 S312 H P G D L K N S V E V A L N K
Rat Rattus norvegicus Q4KM49 528 59097 S312 H P G D L K N S V E V A L N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ08 527 59266 S312 H P G D L K N S V E A A L N K
Frog Xenopus laevis Q7ZX51 528 58855 S312 H P G D L K A S V E K A L N K
Zebra Danio Brachydanio rerio Q6TGS6 529 59515 S312 H P G D L K A S V E L A L N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648895 525 58141 T314 H P G D L K A T V E K Y I N R
Honey Bee Apis mellifera XP_397348 646 73740 I430 N A F A K E E I H P G D L K N
Nematode Worm Caenorhab. elegans Q20970 917 101695 T674 D G E N K Q L T I D V K T L Q
Sea Urchin Strong. purpuratus XP_787967 524 58523 A308 H P G D L K A A V T R E L N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SVN5 797 89835 R580 N D E V A R Y R E K F A G S Q
Baker's Yeast Sacchar. cerevisiae P36421 394 44001 A212 S L G Y K K R A H L M N P M V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.6 92.4 N.A. 96.5 95 N.A. N.A. 87.1 79.7 81.6 N.A. 67.4 56.3 25.8 67.4
Protein Similarity: 100 100 96.7 95.2 N.A. 99 98.4 N.A. N.A. 93.5 90.7 91.4 N.A. 79.5 65.6 38.5 81.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 86.6 N.A. 60 6.6 6.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 93.3 N.A. 80 20 46.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 25.8 42.4 N.A.
Protein Similarity: N.A. N.A. N.A. 39.6 56.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 0 27 14 0 0 7 67 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 74 0 0 0 0 0 7 0 7 0 0 0 % D
% Glu: 0 0 14 0 0 7 7 0 7 67 0 7 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 7 80 0 0 0 0 0 0 0 7 0 7 0 0 % G
% His: 74 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 7 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 20 80 0 0 0 7 14 7 0 7 67 % K
% Leu: 0 7 0 0 74 0 7 0 0 7 7 0 74 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % M
% Asn: 14 0 0 7 0 0 47 0 0 0 0 7 0 74 7 % N
% Pro: 0 74 0 0 0 0 0 0 0 7 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 14 % Q
% Arg: 0 0 0 0 0 7 7 7 0 0 7 0 0 0 7 % R
% Ser: 7 0 0 0 0 0 0 60 0 0 0 0 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 14 0 7 0 0 7 0 0 % T
% Val: 0 0 0 7 0 0 0 0 74 0 47 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 7 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _