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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YARS All Species: 25.45
Human Site: S345 Identified Species: 40
UniProt: P54577 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54577 NP_003671.1 528 59143 S345 S A A Y P D P S K Q K P M A K
Chimpanzee Pan troglodytes XP_524651 528 59111 S345 S A A Y P D P S K Q K P M A K
Rhesus Macaque Macaca mulatta XP_001104797 526 58788 S343 S A A Y P D P S K Q K P M A K
Dog Lupus familis XP_535324 511 57292 S328 S A A Y P D P S K Q K P V A K
Cat Felis silvestris
Mouse Mus musculus Q91WQ3 528 59087 S345 S A A Y P D P S K Q K P P A K
Rat Rattus norvegicus Q4KM49 528 59097 S345 S A A Y P D P S K Q K P T A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ08 527 59266 P344 T N A A Y P N P S K A K P A E
Frog Xenopus laevis Q7ZX51 528 58855 S345 N D A Y P D A S K Q K S V P K
Zebra Danio Brachydanio rerio Q6TGS6 529 59515 K346 S A Y P E P S K N K G G V K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648895 525 58141 P344 K L S A A A Y P P P A K V K A
Honey Bee Apis mellifera XP_397348 646 73740 K461 F E T D S K F K N L A N K A Y
Nematode Worm Caenorhab. elegans Q20970 917 101695 K737 P S E P K K A K E Q K K G K G
Sea Urchin Strong. purpuratus XP_787967 524 58523 K342 Q A Y P P P P K K R A A K G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SVN5 797 89835 A616 S D A K K Q K A S S K G G G K
Baker's Yeast Sacchar. cerevisiae P36421 394 44001 E242 S K I D L L E E P K Q V K K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.6 92.4 N.A. 96.5 95 N.A. N.A. 87.1 79.7 81.6 N.A. 67.4 56.3 25.8 67.4
Protein Similarity: 100 100 96.7 95.2 N.A. 99 98.4 N.A. N.A. 93.5 90.7 91.4 N.A. 79.5 65.6 38.5 81.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 13.3 60 13.3 N.A. 0 6.6 13.3 26.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 33.3 73.3 26.6 N.A. 13.3 6.6 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 25.8 42.4 N.A.
Protein Similarity: N.A. N.A. N.A. 39.6 56.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 60 14 7 7 14 7 0 0 27 7 0 54 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 14 0 47 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 7 0 7 0 7 7 7 0 0 0 0 0 7 % E
% Phe: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 7 14 14 14 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 7 0 7 14 14 7 27 54 20 60 20 20 27 60 % K
% Leu: 0 7 0 0 7 7 0 0 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % M
% Asn: 7 7 0 0 0 0 7 0 14 0 0 7 0 0 0 % N
% Pro: 7 0 0 20 54 20 47 14 14 7 0 40 14 7 0 % P
% Gln: 7 0 0 0 0 7 0 0 0 54 7 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % R
% Ser: 60 7 7 0 7 0 7 47 14 7 0 7 0 0 0 % S
% Thr: 7 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 7 27 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 14 47 7 0 7 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _