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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YARS All Species: 19.39
Human Site: S516 Identified Species: 30.48
UniProt: P54577 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54577 NP_003671.1 528 59143 S516 N F M T K L G S I S C K S L K
Chimpanzee Pan troglodytes XP_524651 528 59111 S516 N F M T K L G S I S C K S L K
Rhesus Macaque Macaca mulatta XP_001104797 526 58788 S514 N F M T K L G S I S C K S L K
Dog Lupus familis XP_535324 511 57292 C499 N F M T K L G C V S C K S L K
Cat Felis silvestris
Mouse Mus musculus Q91WQ3 528 59087 F516 N F M T K L G F V S C K S L K
Rat Rattus norvegicus Q4KM49 528 59097 F516 N F M T K L G F V S C K S L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ08 527 59266 S515 N F L T K L G S I S C K S L K
Frog Xenopus laevis Q7ZX51 528 58855 S516 N F L T K L G S V T C K T L R
Zebra Danio Brachydanio rerio Q6TGS6 529 59515 R517 N L M T K L G R I T C K T L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648895 525 58141 E513 F L L T P E G E K L S S K L A
Honey Bee Apis mellifera XP_397348 646 73740 T629 W S G N L L L T A N G G K L T
Nematode Worm Caenorhab. elegans Q20970 917 101695 K905 L L I G S E S K M T A P T L R
Sea Urchin Strong. purpuratus XP_787967 524 58523 I512 P F Q T K L G I I K A P T L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SVN5 797 89835 V785 P F T T S A G V C K V S S I S
Baker's Yeast Sacchar. cerevisiae P36421 394 44001 N383 Y P G A T K T N E I A T K L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.6 92.4 N.A. 96.5 95 N.A. N.A. 87.1 79.7 81.6 N.A. 67.4 56.3 25.8 67.4
Protein Similarity: 100 100 96.7 95.2 N.A. 99 98.4 N.A. N.A. 93.5 90.7 91.4 N.A. 79.5 65.6 38.5 81.4
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. 93.3 66.6 73.3 N.A. 20 13.3 6.6 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 100 100 86.6 N.A. 26.6 26.6 40 60
Percent
Protein Identity: N.A. N.A. N.A. 25.8 42.4 N.A.
Protein Similarity: N.A. N.A. N.A. 39.6 56.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 0 0 7 0 20 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 7 7 0 60 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 14 0 7 7 0 0 0 0 0 7 % E
% Phe: 7 67 0 0 0 0 0 14 0 0 0 0 0 0 0 % F
% Gly: 0 0 14 7 0 0 80 0 0 0 7 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 7 40 7 0 0 0 7 0 % I
% Lys: 0 0 0 0 67 7 0 7 7 14 0 60 20 0 60 % K
% Leu: 7 20 20 0 7 74 7 0 0 7 0 0 0 94 0 % L
% Met: 0 0 47 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 60 0 0 7 0 0 0 7 0 7 0 0 0 0 0 % N
% Pro: 14 7 0 0 7 0 0 0 0 0 0 14 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 14 % R
% Ser: 0 7 0 0 14 0 7 34 0 47 7 14 54 0 7 % S
% Thr: 0 0 7 80 7 0 7 7 0 20 0 7 27 0 7 % T
% Val: 0 0 0 0 0 0 0 7 27 0 7 0 0 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _