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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
38.48
Human Site:
T360
Identified Species:
56.44
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
T360
L
D
M
Y
E
L
C
T
P
E
L
Q
E
K
M
Chimpanzee
Pan troglodytes
P60051
493
55922
T360
L
D
M
Y
E
L
C
T
P
E
L
Q
E
K
M
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
Q329
E
L
C
T
P
E
L
Q
E
K
M
V
S
F
R
Dog
Lupus familis
XP_537306
545
61461
T411
L
D
V
Y
E
L
C
T
P
E
L
Q
E
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
T360
L
D
V
Y
E
L
C
T
P
E
L
Q
E
K
M
Rat
Rattus norvegicus
NP_001008302
493
55958
T360
L
D
V
Y
E
L
C
T
P
E
L
Q
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
E302
L
C
T
P
E
L
Q
E
K
M
V
S
F
R
S
Chicken
Gallus gallus
XP_419150
492
55612
T358
L
D
V
Y
E
L
C
T
P
D
L
Q
E
K
M
Frog
Xenopus laevis
Q6GNI6
523
60030
G356
N
G
E
S
H
V
S
G
T
T
T
L
T
D
C
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S365
S
S
A
K
I
K
C
S
G
C
H
S
Y
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
L345
I
D
F
D
A
F
E
L
C
T
P
E
L
Q
N
Honey Bee
Apis mellifera
XP_395043
497
56311
S355
F
D
V
F
E
L
C
S
S
E
L
Q
N
K
L
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
D335
L
C
S
Q
E
L
K
D
K
L
V
A
R
R
A
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
S361
L
D
T
Y
E
L
C
S
P
E
L
Q
E
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
S340
L
D
I
F
D
L
C
S
E
D
L
R
K
K
L
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
T346
L
D
V
A
D
M
L
T
P
E
Y
A
A
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
20
86.6
0
6.6
N.A.
6.6
53.3
20
80
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
33.3
100
6.6
20
N.A.
26.6
80
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
0
0
0
0
0
0
13
7
0
7
% A
% Cys:
0
13
7
0
0
0
63
0
7
7
0
0
0
0
7
% C
% Asp:
0
69
0
7
13
0
0
7
0
13
0
0
0
7
0
% D
% Glu:
7
0
7
0
63
7
7
7
13
50
0
7
44
7
7
% E
% Phe:
7
0
7
13
0
7
0
0
0
0
0
0
7
7
0
% F
% Gly:
0
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
7
7
0
13
7
0
0
7
57
7
% K
% Leu:
69
7
0
0
0
69
13
7
0
7
57
7
7
0
19
% L
% Met:
0
0
13
0
0
7
0
0
0
7
7
0
0
0
38
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% N
% Pro:
0
0
0
7
7
0
0
0
50
0
7
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
7
7
0
0
0
50
0
13
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
7
13
7
% R
% Ser:
7
7
7
7
0
0
7
25
7
0
0
13
7
0
7
% S
% Thr:
0
0
13
7
0
0
0
44
7
13
7
0
7
0
0
% T
% Val:
0
0
38
0
0
7
0
0
0
0
13
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
44
0
0
0
0
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _