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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
21.82
Human Site:
T86
Identified Species:
32
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
T86
P
E
E
P
S
A
K
T
V
F
V
E
D
M
T
Chimpanzee
Pan troglodytes
P60051
493
55922
T86
P
E
E
P
S
A
K
T
V
F
V
E
D
M
T
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
M81
N
L
G
N
T
C
Y
M
N
A
T
V
Q
C
I
Dog
Lupus familis
XP_537306
545
61461
T137
P
E
E
P
S
A
K
T
V
F
V
E
D
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
T86
P
E
E
P
S
A
K
T
V
F
V
E
D
M
T
Rat
Rattus norvegicus
NP_001008302
493
55958
T86
P
E
E
P
S
A
K
T
V
F
V
E
D
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
M54
N
L
G
N
T
C
Y
M
N
A
T
V
Q
C
I
Chicken
Gallus gallus
XP_419150
492
55612
P86
P
E
E
P
I
A
R
P
V
F
V
E
D
M
T
Frog
Xenopus laevis
Q6GNI6
523
60030
Q99
G
I
Y
C
F
M
C
Q
D
Y
I
Y
D
K
D
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
D104
V
C
Q
D
Y
I
Y
D
K
D
M
E
Q
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
V85
P
E
V
P
A
T
P
V
K
F
I
E
D
M
N
Honey Bee
Apis mellifera
XP_395043
497
56311
P87
P
A
E
P
T
E
K
P
L
F
L
E
D
M
N
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
K85
P
P
T
V
L
E
K
K
Q
A
N
R
D
K
Q
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
T86
P
E
A
P
Q
E
K
T
V
F
V
E
D
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
I85
V
K
A
P
E
K
A
I
V
F
A
E
D
L
P
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
N90
S
K
P
A
K
K
N
N
F
I
E
D
L
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
80
6.6
6.6
N.A.
46.6
53.3
20
80
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
86.6
20
26.6
N.A.
60
73.3
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
13
7
7
38
7
0
0
19
7
0
0
7
7
% A
% Cys:
0
7
0
7
0
13
7
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
7
0
0
0
7
7
7
0
7
75
0
7
% D
% Glu:
0
50
44
0
7
19
0
0
0
0
7
69
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
7
63
0
0
0
0
0
% F
% Gly:
7
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
7
0
7
0
7
13
0
0
7
13
% I
% Lys:
0
13
0
0
7
13
50
7
13
0
0
0
0
13
0
% K
% Leu:
0
13
0
0
7
0
0
0
7
0
7
0
7
7
0
% L
% Met:
0
0
0
0
0
7
0
13
0
0
7
0
0
57
0
% M
% Asn:
13
0
0
13
0
0
7
7
13
0
7
0
0
0
13
% N
% Pro:
63
7
7
63
0
0
7
13
0
0
0
0
0
0
13
% P
% Gln:
0
0
7
0
7
0
0
7
7
0
0
0
19
0
7
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% R
% Ser:
7
0
0
0
32
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
19
7
0
38
0
0
13
0
0
0
44
% T
% Val:
13
0
7
7
0
0
0
7
50
0
44
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
19
0
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _