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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
28.79
Human Site:
Y401
Identified Species:
42.22
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
Y401
S
P
Q
K
E
V
K
Y
E
P
F
S
F
A
D
Chimpanzee
Pan troglodytes
P60051
493
55922
Y401
S
P
Q
K
E
V
K
Y
E
P
F
S
F
A
D
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
F369
K
E
V
K
Y
E
P
F
S
F
A
D
D
I
G
Dog
Lupus familis
XP_537306
545
61461
Y452
S
P
Q
K
E
V
K
Y
E
P
F
S
F
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
Y400
S
P
P
K
E
I
K
Y
E
P
F
S
F
A
D
Rat
Rattus norvegicus
NP_001008302
493
55958
Y400
S
P
P
K
E
I
K
Y
E
P
F
S
F
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
S342
E
V
K
Y
E
P
F
S
F
P
D
D
I
G
S
Chicken
Gallus gallus
XP_419150
492
55612
Y399
G
A
Q
K
E
V
K
Y
E
P
F
S
F
P
D
Frog
Xenopus laevis
Q6GNI6
523
60030
K398
T
K
Q
L
T
M
K
K
L
P
I
V
A
C
F
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
P410
I
T
T
Y
V
S
F
P
L
E
L
D
M
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
D385
E
P
N
E
E
K
K
D
V
K
Y
E
Q
F
W
Honey Bee
Apis mellifera
XP_395043
497
56311
Q398
D
S
K
K
K
V
K
Q
E
S
F
W
F
P
D
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
A375
K
I
F
D
D
G
V
A
L
P
T
A
F
E
D
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
Y412
E
P
K
K
D
V
K
Y
L
P
Y
D
F
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
T380
K
D
S
D
V
K
M
T
D
A
E
A
S
A
N
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
T396
T
P
R
E
Q
Y
E
T
Q
V
A
L
N
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
6.6
100
N.A.
86.6
86.6
N.A.
13.3
80
20
0
N.A.
20
46.6
20
53.3
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
20
80
33.3
0
N.A.
33.3
60
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
7
0
7
13
13
7
38
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
7
0
13
13
0
0
7
7
0
7
25
7
0
57
% D
% Glu:
19
7
0
13
50
7
7
0
44
7
7
7
0
13
0
% E
% Phe:
0
0
7
0
0
0
13
7
7
7
44
0
57
7
7
% F
% Gly:
7
0
0
0
0
7
0
0
0
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
13
0
0
0
0
7
0
7
7
0
% I
% Lys:
19
7
19
57
7
13
63
7
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
25
0
7
7
0
0
0
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
7
% N
% Pro:
0
50
13
0
0
7
7
7
0
63
0
0
0
19
7
% P
% Gln:
0
0
32
0
7
0
0
7
7
0
0
0
7
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
32
7
7
0
0
7
0
7
7
7
0
38
7
0
13
% S
% Thr:
13
7
7
0
7
0
0
13
0
0
7
0
0
7
0
% T
% Val:
0
7
7
0
13
38
7
0
7
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% W
% Tyr:
0
0
0
13
7
7
0
44
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _