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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAG1
All Species:
23.64
Human Site:
Y121
Identified Species:
52
UniProt:
P54619
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54619
NP_002724.1
331
37579
Y121
I
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
Chimpanzee
Pan troglodytes
XP_509039
361
41042
Y151
I
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
Rhesus Macaque
Macaca mulatta
XP_001105687
331
37575
Y121
I
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
Dog
Lupus familis
XP_543685
330
37441
Y121
I
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O54950
330
37502
L121
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
L
Rat
Rattus norvegicus
P80385
330
37368
L121
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513132
599
66421
Y383
I
E
T
W
R
E
L
Y
L
Q
E
T
F
K
P
Chicken
Gallus gallus
NP_001029999
276
31311
S79
F
K
P
L
V
C
I
S
P
N
A
S
L
F
D
Frog
Xenopus laevis
NP_001085968
334
37763
Y122
I
E
T
W
R
E
L
Y
L
Q
D
S
F
K
P
Zebra Danio
Brachydanio rerio
NP_998326
330
37280
V128
Q
D
S
F
K
P
L
V
S
I
S
P
N
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12904
322
36383
L121
R
A
L
G
V
D
Q
L
D
T
A
S
I
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.6
98.4
N.A.
96.9
96
N.A.
43.2
76.1
80.5
79.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
100
98.7
N.A.
99.4
98.7
N.A.
49.7
80.3
88.6
87
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
80
6.6
93.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
0
0
N.A.
100
20
100
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
19
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
0
10
19
46
0
0
0
10
% D
% Glu:
19
55
0
0
19
55
0
0
0
0
10
0
0
0
0
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
19
55
10
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
55
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
0
0
19
55
0
% K
% Leu:
0
0
10
10
0
0
28
28
55
0
0
0
10
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
10
0
0
10
0
19
64
% P
% Gln:
10
0
0
0
0
0
10
0
19
55
0
0
0
0
0
% Q
% Arg:
10
0
0
19
55
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
10
10
0
28
64
0
0
10
% S
% Thr:
0
19
55
0
0
0
0
0
0
10
0
10
0
0
0
% T
% Val:
0
0
0
0
19
19
37
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
19
55
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _