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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
14.55
Human Site:
S305
Identified Species:
26.67
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
S305
E
K
F
E
C
T
E
S
E
V
M
N
S
L
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
E307
E
K
F
E
C
S
E
E
E
V
L
S
C
L
Y
Dog
Lupus familis
XP_546691
722
81319
S475
E
K
F
E
C
T
E
S
E
V
M
N
S
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
S305
E
K
F
E
C
T
E
S
E
V
M
N
S
L
Y
Rat
Rattus norvegicus
Q09137
552
62239
S305
E
K
F
E
C
T
E
S
E
V
M
N
S
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
E276
E
K
F
E
C
T
E
E
E
V
L
S
C
L
Y
Chicken
Gallus gallus
Q9IA88
798
88848
E382
P
Q
D
S
L
T
S
E
T
L
R
S
S
L
L
Frog
Xenopus laevis
NP_001088426
560
64038
E316
D
K
C
E
C
T
E
E
E
V
L
S
C
L
Y
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Q399
P
R
P
L
Y
P
L
Q
D
Q
S
N
A
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
K273
K
K
H
E
W
F
Q
K
D
L
P
S
Y
L
F
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
Y373
E
V
T
E
F
Q
R
Y
H
V
A
E
E
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
A296
R
Q
H
P
W
F
Q
A
H
L
P
R
Y
L
A
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I363
M
G
Y
E
K
D
E
I
Y
E
S
L
E
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
66.6
100
N.A.
100
100
N.A.
73.3
20
60
6.6
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
100
N.A.
86.6
40
80
33.3
N.A.
N.A.
60
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
8
% A
% Cys:
0
0
8
0
54
0
0
0
0
0
0
0
24
0
0
% C
% Asp:
8
0
8
0
0
8
0
0
16
0
0
0
0
0
0
% D
% Glu:
54
0
0
77
0
0
62
31
54
8
0
8
16
8
0
% E
% Phe:
0
0
47
0
8
16
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
62
0
0
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
8
0
8
0
0
24
24
8
0
77
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% N
% Pro:
16
0
8
8
0
8
0
0
0
0
16
0
0
0
0
% P
% Gln:
0
16
0
0
0
8
16
8
0
8
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
8
0
0
0
8
8
0
0
0
% R
% Ser:
0
0
0
8
0
8
8
31
0
0
16
39
39
8
16
% S
% Thr:
0
0
8
0
0
54
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
62
0
0
0
8
8
% V
% Trp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
8
8
0
0
0
16
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _