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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
25.15
Human Site:
Y312
Identified Species:
46.11
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
Y312
S
E
V
M
N
S
L
Y
S
G
D
P
Q
D
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
Y314
E
E
V
L
S
C
L
Y
N
R
N
H
Q
D
P
Dog
Lupus familis
XP_546691
722
81319
Y482
S
E
V
M
N
S
L
Y
S
G
D
P
Q
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
Y312
S
E
V
M
N
S
L
Y
S
G
D
P
Q
D
Q
Rat
Rattus norvegicus
Q09137
552
62239
Y312
S
E
V
M
N
S
L
Y
S
G
D
P
Q
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
Y283
E
E
V
L
S
C
L
Y
S
R
N
H
Q
D
P
Chicken
Gallus gallus
Q9IA88
798
88848
L389
E
T
L
R
S
S
L
L
Y
Q
Q
P
Q
S
L
Frog
Xenopus laevis
NP_001088426
560
64038
Y323
E
E
V
L
S
C
L
Y
S
H
N
H
Q
D
P
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S406
Q
D
Q
S
N
A
V
S
M
T
V
P
Q
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
F280
K
D
L
P
S
Y
L
F
P
S
P
V
E
Q
D
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
V380
Y
H
V
A
E
E
E
V
T
S
A
L
L
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
A303
A
H
L
P
R
Y
L
A
V
P
P
P
D
T
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S370
I
Y
E
S
L
E
S
S
E
D
T
P
A
F
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
40
100
N.A.
100
100
N.A.
46.6
26.6
46.6
26.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
100
N.A.
66.6
100
N.A.
100
100
N.A.
66.6
40
66.6
46.6
N.A.
N.A.
40
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
0
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
0
0
0
0
8
31
0
8
54
16
% D
% Glu:
31
54
8
0
8
16
8
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
31
0
0
0
8
0
% G
% His:
0
16
0
0
0
0
0
0
0
8
0
24
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
24
24
8
0
77
8
0
0
0
8
8
0
8
% L
% Met:
0
0
0
31
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
39
0
0
0
8
0
24
0
0
0
8
% N
% Pro:
0
0
0
16
0
0
0
0
8
8
16
62
0
0
24
% P
% Gln:
8
0
8
0
0
0
0
0
0
8
8
0
70
8
39
% Q
% Arg:
0
0
0
8
8
0
0
0
0
16
0
0
0
0
0
% R
% Ser:
31
0
0
16
39
39
8
16
47
16
0
0
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
8
8
8
0
0
8
0
% T
% Val:
0
0
62
0
0
0
8
8
8
0
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
16
0
54
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _