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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA2
All Species:
38.79
Human Site:
T422
Identified Species:
94.81
UniProt:
P54652
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54652
NP_068814.2
639
70021
T422
P
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537479
637
69865
T422
P
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P17156
633
69722
T422
P
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Rat
Rattus norvegicus
P14659
633
69623
T422
P
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507710
635
69710
T422
P
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Chicken
Gallus gallus
P08106
634
69732
T422
A
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Frog
Xenopus laevis
P02827
647
70897
T420
V
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Zebra Danio
Brachydanio rerio
Q90473
649
70955
T419
V
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11147
651
71113
T419
V
L
I
K
R
N
T
T
I
P
T
K
Q
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P09446
640
69704
T420
A
L
I
K
R
N
T
T
I
P
T
K
T
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.2
N.A.
98.2
98.5
N.A.
96
91.5
82.2
84.9
N.A.
82.1
N.A.
82.1
N.A.
Protein Similarity:
100
N.A.
N.A.
99.3
N.A.
98.5
98.7
N.A.
97.8
95.6
91.5
91.8
N.A.
89.8
N.A.
89.8
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
93.3
N.A.
80
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
93.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
100
0
0
0
0
0
100
0
0
0
0
0
0
% I
% Lys:
0
0
0
100
0
0
0
0
0
0
0
100
0
0
0
% K
% Leu:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
90
0
100
% Q
% Arg:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
100
100
0
0
100
0
10
90
0
% T
% Val:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _