Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 43.03
Human Site: S172 Identified Species: 72.82
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 S172 T F I G T E P S L G V K K P T
Chimpanzee Pan troglodytes XP_001143074 641 71273 S427 T F I G T E P S L G V K K P T
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 S177 T F I G T E P S L G V K K P T
Dog Lupus familis XP_543760 437 48223 S223 T F I G T E P S L G V K K P T
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 S172 T F I G T E P S L G V K K P S
Rat Rattus norvegicus P54690 411 46027 S197 T F I G I E P S L G V K K P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 S146 T L I G T E P S L G V K K P T
Chicken Gallus gallus XP_416424 386 43007 S172 T L I G T E P S L G V K K P T
Frog Xenopus laevis NP_001087994 394 43966 T178 T F I G T E P T L G V R K P S
Zebra Danio Brachydanio rerio NP_956358 385 42673 T173 T L L G T E P T L G V K K P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 T195 T L I G T D P T L G V G C A T
Sea Urchin Strong. purpuratus XP_788267 391 44250 M180 S R T S S L Y M R P T F I G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 P195 N K R W I P P P G K G S L Y I
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 G153 T L I G T T A G L G V S T P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. 93.3 93.3 80 73.3 N.A. N.A. N.A. 60 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 93.3 93.3 100 93.3 N.A. N.A. N.A. 73.3 20
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 72 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 50 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 86 0 0 0 8 8 86 8 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 79 0 15 0 0 0 0 0 0 0 8 0 8 % I
% Lys: 0 8 0 0 0 0 0 0 0 8 0 65 72 0 0 % K
% Leu: 0 36 8 0 0 8 0 0 86 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 86 8 0 8 0 0 0 79 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 0 0 0 0 0 8 0 0 8 0 0 0 % R
% Ser: 8 0 0 8 8 0 0 58 0 0 0 15 0 0 29 % S
% Thr: 86 0 8 0 79 8 0 22 0 0 8 0 8 0 58 % T
% Val: 0 0 0 0 0 0 0 0 0 0 86 0 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _