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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 20.61
Human Site: S18 Identified Species: 34.87
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 S18 E C T G E G G S K E V V G T F
Chimpanzee Pan troglodytes XP_001143074 641 71273 S273 E C T G E G G S K E V V G T F
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 S23 E G T G E G G S K E V V G S F
Dog Lupus familis XP_543760 437 48223 S69 E C T G E A G S K E M V G T F
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 S18 P F A G E R G S E E V A E T F
Rat Rattus norvegicus P54690 411 46027 S43 S Y D E E G G S E A S T Q T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 P18 V L K E K P D P E S L V F G T
Chicken Gallus gallus XP_416424 386 43007 T18 G G C S E E A T K Y V T E S F
Frog Xenopus laevis NP_001087994 394 43966 P24 N G C S N G D P G V T S D S F
Zebra Danio Brachydanio rerio NP_956358 385 42673 M19 S S H K E N G M A D S A S S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 R41 E I H K E Y D R K K T F Y H R
Sea Urchin Strong. purpuratus XP_788267 391 44250 V36 S V C A V R C V H S N H D S F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 S58 I S S N F I V S E V S R N R R
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 N25 H A S K P K P N S E L V F G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 86.6 86.6 N.A. 53.3 40 N.A. 6.6 26.6 13.3 20 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 60 46.6 N.A. 26.6 40 20 33.3 N.A. N.A. N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 0 8 8 0 8 8 0 15 0 0 0 % A
% Cys: 0 22 22 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 22 0 0 8 0 0 15 0 0 % D
% Glu: 36 0 0 15 65 8 0 0 29 43 0 0 15 0 0 % E
% Phe: 0 8 0 0 8 0 0 0 0 0 0 8 15 0 72 % F
% Gly: 8 22 0 36 0 36 50 0 8 0 0 0 29 15 0 % G
% His: 8 0 15 0 0 0 0 0 8 0 0 8 0 8 0 % H
% Ile: 8 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 22 8 8 0 0 43 8 0 0 0 0 8 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 15 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % M
% Asn: 8 0 0 8 8 8 0 8 0 0 8 0 8 0 0 % N
% Pro: 8 0 0 0 8 8 8 15 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 15 0 8 0 0 0 8 0 8 15 % R
% Ser: 22 15 15 15 0 0 0 50 8 15 22 8 8 36 0 % S
% Thr: 0 0 29 0 0 0 0 8 0 0 15 15 0 36 8 % T
% Val: 8 8 0 0 8 0 8 8 0 15 36 43 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 0 0 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _