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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 34.85
Human Site: S230 Identified Species: 58.97
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 S230 M G G N Y G S S L F A Q C E A
Chimpanzee Pan troglodytes XP_001143074 641 71273 S485 M G G N Y G S S L F A Q C E A
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 S235 M G G N Y G S S L F A Q C E A
Dog Lupus familis XP_543760 437 48223 S281 M G G N Y G S S L F A Q C E A
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 S230 M G G N Y G A S L L A Q C E A
Rat Rattus norvegicus P54690 411 46027 S255 M G C N Y G S S L L A Q C E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 S204 M G G N Y G S S I F A Q R E A
Chicken Gallus gallus XP_416424 386 43007 S230 L G G N Y G S S I C A Q Q E A
Frog Xenopus laevis NP_001087994 394 43966 T236 V G G N Y G P T I F A Q Y E A
Zebra Danio Brachydanio rerio NP_956358 385 42673 I231 G G N Y G S S I Y A Q Y E A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 I253 G C N Y A P T I W V G K E A A
Sea Urchin Strong. purpuratus XP_788267 391 44250 Y238 A W H G G V G Y A K M G S N Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 T253 E T E F H R A T P G G T G G V
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 V211 G A N Y A P C V L P Q L Q A A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 86.6 73.3 66.6 13.3 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 93.3 86.6 86.6 13.3 N.A. N.A. N.A. 20 0
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 15 0 15 0 8 8 65 0 0 22 79 % A
% Cys: 0 8 8 0 0 0 8 0 0 8 0 0 43 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 8 0 0 0 0 0 0 0 0 0 15 65 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 43 0 0 0 0 0 % F
% Gly: 22 72 58 8 15 65 8 0 0 8 15 8 8 8 0 % G
% His: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 15 22 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 50 15 0 8 0 0 0 % L
% Met: 50 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 22 65 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 15 8 0 8 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 15 65 15 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 8 58 58 0 0 0 0 8 0 0 % S
% Thr: 0 8 0 0 0 0 8 15 0 0 0 8 0 0 0 % T
% Val: 8 0 0 0 0 8 0 8 0 8 0 0 0 0 15 % V
% Trp: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 22 65 0 0 8 8 0 0 8 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _