Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 30.61
Human Site: S363 Identified Species: 51.79
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 S363 E N G P K L A S R I L S K L T
Chimpanzee Pan troglodytes XP_001143074 641 71273 S618 E N G P K L A S R I L S K L T
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 S368 E N G A K L A S R I L S K L T
Dog Lupus familis XP_543760 437 48223 G414 E N G P K L A G R I L D K L T
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 S363 E N G P K L A S R I L G K L T
Rat Rattus norvegicus P54690 411 46027 S388 E N G H K L S S R I M A K L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 T337 D N G P E L T T R L L D Q L T
Chicken Gallus gallus XP_416424 386 43007 T363 E N G P Q L T T Q I L N K L T
Frog Xenopus laevis NP_001087994 394 43966 K369 E N G P K M A K R F L Q E L T
Zebra Danio Brachydanio rerio NP_956358 385 42673 S363 G S F P P L A S R L L K E L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 S386 L H I P T M S S K F G V M Q K
Sea Urchin Strong. purpuratus XP_788267 391 44250 M367 K V L F K G D M I D I P T M D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 Q391 G F G T V S K Q L Y T S L T S
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 L347 P G E Q T G P L A K E V A Q W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 73.3 N.A. 53.3 66.6 66.6 53.3 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 86.6 93.3 80 73.3 N.A. N.A. N.A. 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 50 0 8 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 0 8 0 15 0 0 8 % D
% Glu: 58 0 8 0 8 0 0 0 0 0 8 0 15 0 0 % E
% Phe: 0 8 8 8 0 0 0 0 0 15 0 0 0 0 0 % F
% Gly: 15 8 72 0 0 15 0 8 0 0 8 8 0 0 0 % G
% His: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 50 8 0 0 0 0 % I
% Lys: 8 0 0 0 58 0 8 8 8 8 0 8 50 0 8 % K
% Leu: 8 0 8 0 0 65 0 8 8 15 65 0 8 72 0 % L
% Met: 0 0 0 0 0 15 0 8 0 0 8 0 8 8 0 % M
% Asn: 0 65 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 0 0 65 8 0 8 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 8 8 0 0 8 8 15 0 % Q
% Arg: 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 8 15 50 0 0 0 29 0 0 8 % S
% Thr: 0 0 0 8 15 0 15 15 0 0 8 0 8 8 72 % T
% Val: 0 8 0 0 8 0 0 0 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _