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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 29.39
Human Site: S379 Identified Species: 49.74
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 S379 I Q Y G R E E S D W T I V L S
Chimpanzee Pan troglodytes XP_001143074 641 71273 S634 I Q Y G R E E S D W T I V L S
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 S384 I Q Y G R E E S D W T I V L S
Dog Lupus familis XP_543760 437 48223 S430 I Q Y G R E E S D W T I I V S
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 S379 I Q Y G R V E S D W T I E L P
Rat Rattus norvegicus P54690 411 46027 S404 I Q Y G R I K S E W T L E L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 L353 I Q V T L S L L E V L K G Q V
Chicken Gallus gallus XP_416424 386 43007 S379 I Q Y G R E D S D W T V L V S
Frog Xenopus laevis NP_001087994 394 43966 S385 I Q Y G R A A S D W M V E V P
Zebra Danio Brachydanio rerio NP_956358 385 42673
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 Q402 Y N T I N D I Q Y G R I I K D
Sea Urchin Strong. purpuratus XP_788267 391 44250 F383 G A E L C K R F Y N T L M D I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 N407 Q M G L S E D N M N W T V Q L
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 T363 N G I Q Y G E T E H G N W S R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 100 86.6 N.A. 80 60 N.A. 13.3 73.3 53.3 0 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 80 80 N.A. 20 100 66.6 0 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 15 0 50 0 0 0 0 8 8 % D
% Glu: 0 0 8 0 0 43 43 0 22 0 0 0 22 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 8 8 58 0 8 0 0 0 8 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 65 0 8 8 0 8 8 0 0 0 0 43 15 0 8 % I
% Lys: 0 0 0 0 0 8 8 0 0 0 0 8 0 8 0 % K
% Leu: 0 0 0 15 8 0 8 8 0 0 8 15 8 36 8 % L
% Met: 0 8 0 0 0 0 0 0 8 0 8 0 8 0 0 % M
% Asn: 8 8 0 0 8 0 0 8 0 15 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 % P
% Gln: 8 65 0 8 0 0 0 8 0 0 0 0 0 15 0 % Q
% Arg: 0 0 0 0 58 0 8 0 0 0 8 0 0 0 8 % R
% Ser: 0 0 0 0 8 8 0 58 0 0 0 0 0 8 36 % S
% Thr: 0 0 8 8 0 0 0 8 0 0 58 8 0 0 0 % T
% Val: 0 0 8 0 0 8 0 0 0 8 0 15 29 22 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 58 8 0 8 0 0 % W
% Tyr: 8 0 58 0 8 0 0 0 15 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _