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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 30.91
Human Site: T128 Identified Species: 52.31
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 T128 Y R S A V R A T L P V F D K E
Chimpanzee Pan troglodytes XP_001143074 641 71273 T383 Y R S A V R A T L P V F D K E
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 T133 Y R S A V R A T L P V F D K E
Dog Lupus familis XP_543760 437 48223 T179 H R S A L R A T L P V F D K E
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 T128 C R S A V R T T L P M F D K E
Rat Rattus norvegicus P54690 411 46027 T153 C R S A V R T T L P E F D K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 L111 P E F D K E E L L Q C I V Q L
Chicken Gallus gallus XP_416424 386 43007 T128 A R S A R R M T L P C F D Q N
Frog Xenopus laevis NP_001087994 394 43966 T134 H R S S L R M T L P D F D K E
Zebra Danio Brachydanio rerio NP_956358 385 42673 C129 L K S A H R A C L P S F D C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 A151 K R T A L R A A L P D F D S E
Sea Urchin Strong. purpuratus XP_788267 391 44250 S146 N N S A E R A S L P R F S G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 R161 E E N A I R M R N G A E R M C
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 L118 P T F D P E E L I T L I G K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 6.6 60 66.6 53.3 N.A. N.A. N.A. 60 53.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 80 N.A. 13.3 66.6 86.6 60 N.A. N.A. N.A. 73.3 60
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 79 0 0 50 8 0 0 8 0 0 0 8 % A
% Cys: 15 0 0 0 0 0 0 8 0 0 15 0 0 8 8 % C
% Asp: 0 0 0 15 0 0 0 0 0 0 15 0 72 0 0 % D
% Glu: 8 15 0 0 8 15 15 0 0 0 8 8 0 0 65 % E
% Phe: 0 0 15 0 0 0 0 0 0 0 0 79 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 8 8 0 % G
% His: 15 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 15 0 0 0 % I
% Lys: 8 8 0 0 8 0 0 0 0 0 0 0 0 58 0 % K
% Leu: 8 0 0 0 22 0 0 15 86 0 8 0 0 0 15 % L
% Met: 0 0 0 0 0 0 22 0 0 0 8 0 0 8 0 % M
% Asn: 8 8 8 0 0 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 15 0 0 0 8 0 0 0 0 79 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 15 0 % Q
% Arg: 0 65 0 0 8 86 0 8 0 0 8 0 8 0 0 % R
% Ser: 0 0 72 8 0 0 0 8 0 0 8 0 8 8 0 % S
% Thr: 0 8 8 0 0 0 15 58 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 36 0 0 0 0 0 29 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _