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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT1 All Species: 8.79
Human Site: Y121 Identified Species: 14.87
UniProt: P54687 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54687 NP_005495.2 386 42966 Y121 N L N M D R M Y R S A V R A T
Chimpanzee Pan troglodytes XP_001143074 641 71273 Y376 N L N M D R M Y R S A V R A T
Rhesus Macaque Macaca mulatta XP_001101113 391 43458 Y126 K L N M D R M Y R S A V R A T
Dog Lupus familis XP_543760 437 48223 H172 D L N M D R M H R S A L R A T
Cat Felis silvestris
Mouse Mus musculus P24288 386 42773 C121 D L N M D R M C R S A V R T T
Rat Rattus norvegicus P54690 411 46027 C146 D L N M K R M C R S A V R T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 P104 S A V R A T L P E F D K E E L
Chicken Gallus gallus XP_416424 386 43007 A121 S L N M D R M A R S A R R M T
Frog Xenopus laevis NP_001087994 394 43966 H127 K L N M E R M H R S S L R M T
Zebra Danio Brachydanio rerio NP_956358 385 42673 L122 M L N M K R M L K S A H R A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 K144 E M N M A R M K R T A L R A A
Sea Urchin Strong. purpuratus XP_788267 391 44250 N139 Y D N M E R M N N S A E R A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 E154 N I L L F R P E E N A I R M R
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 P111 S A Q R I C L P T F D P E E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 96.1 82.6 N.A. 84.9 72.5 N.A. 65.5 76.9 69 69.1 N.A. N.A. N.A. 47.9 52.4
Protein Similarity: 100 60 97.6 86.5 N.A. 92.4 84.9 N.A. 73.8 88.3 80.9 81.6 N.A. N.A. N.A. 64.5 68.2
P-Site Identity: 100 100 93.3 80 N.A. 80 73.3 N.A. 0 73.3 60 60 N.A. N.A. N.A. 53.3 53.3
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 80 N.A. 13.3 80 86.6 66.6 N.A. N.A. N.A. 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 46.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 15 0 0 8 0 0 79 0 0 50 8 % A
% Cys: 0 0 0 0 0 8 0 15 0 0 0 0 0 0 8 % C
% Asp: 22 8 0 0 43 0 0 0 0 0 15 0 0 0 0 % D
% Glu: 8 0 0 0 15 0 0 8 15 0 0 8 15 15 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 15 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 15 0 0 0 15 0 0 8 8 0 0 8 0 0 0 % K
% Leu: 0 65 8 8 0 0 15 8 0 0 0 22 0 0 15 % L
% Met: 8 8 0 79 0 0 79 0 0 0 0 0 0 22 0 % M
% Asn: 22 0 79 0 0 0 0 8 8 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 15 0 0 0 8 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 15 0 86 0 0 65 0 0 8 86 0 8 % R
% Ser: 22 0 0 0 0 0 0 0 0 72 8 0 0 0 8 % S
% Thr: 0 0 0 0 0 8 0 0 8 8 0 0 0 15 58 % T
% Val: 0 0 8 0 0 0 0 0 0 0 0 36 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 22 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _