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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCAT1
All Species:
33.64
Human Site:
Y374
Identified Species:
56.92
UniProt:
P54687
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54687
NP_005495.2
386
42966
Y374
S
K
L
T
D
I
Q
Y
G
R
E
E
S
D
W
Chimpanzee
Pan troglodytes
XP_001143074
641
71273
Y629
S
K
L
T
D
I
Q
Y
G
R
E
E
S
D
W
Rhesus Macaque
Macaca mulatta
XP_001101113
391
43458
Y379
S
K
L
T
D
I
Q
Y
G
R
E
E
S
D
W
Dog
Lupus familis
XP_543760
437
48223
Y425
D
K
L
T
D
I
Q
Y
G
R
E
E
S
D
W
Cat
Felis silvestris
Mouse
Mus musculus
P24288
386
42773
Y374
G
K
L
T
D
I
Q
Y
G
R
V
E
S
D
W
Rat
Rattus norvegicus
P54690
411
46027
Y399
A
K
L
T
D
I
Q
Y
G
R
I
K
S
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505701
458
51606
V348
D
Q
L
T
D
I
Q
V
T
L
S
L
L
E
V
Chicken
Gallus gallus
XP_416424
386
43007
Y374
N
K
L
T
D
I
Q
Y
G
R
E
D
S
D
W
Frog
Xenopus laevis
NP_001087994
394
43966
Y380
Q
E
L
T
D
I
Q
Y
G
R
A
A
S
D
W
Zebra Danio
Brachydanio rerio
NP_956358
385
42673
Y374
K
E
L
T
D
I
Q
Y
G
R
T
P
S
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P54688
415
47323
T397
V
M
Q
K
F
Y
N
T
I
N
D
I
Q
Y
G
Sea Urchin
Strong. purpuratus
XP_788267
391
44250
E378
P
T
M
D
N
G
A
E
L
C
K
R
F
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FYA6
415
45563
G402
S
L
T
S
L
Q
M
G
L
S
E
D
N
M
N
Baker's Yeast
Sacchar. cerevisiae
P47176
376
41606
I358
V
A
Q
W
I
N
G
I
Q
Y
G
E
T
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60
96.1
82.6
N.A.
84.9
72.5
N.A.
65.5
76.9
69
69.1
N.A.
N.A.
N.A.
47.9
52.4
Protein Similarity:
100
60
97.6
86.5
N.A.
92.4
84.9
N.A.
73.8
88.3
80.9
81.6
N.A.
N.A.
N.A.
64.5
68.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
73.3
N.A.
33.3
86.6
73.3
73.3
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
46.6
100
80
80
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
46.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.1
62.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
15
0
0
8
72
0
0
0
0
0
8
15
0
58
0
% D
% Glu:
0
15
0
0
0
0
0
8
0
0
43
43
0
22
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
8
8
65
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
72
0
8
8
0
8
8
0
0
0
% I
% Lys:
8
50
0
8
0
0
0
0
0
0
8
8
0
0
0
% K
% Leu:
0
8
72
0
8
0
0
0
15
8
0
8
8
0
0
% L
% Met:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
8
8
8
0
0
8
0
0
8
0
15
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
8
15
0
0
8
72
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
65
0
8
0
0
0
% R
% Ser:
29
0
0
8
0
0
0
0
0
8
8
0
65
0
0
% S
% Thr:
0
8
8
72
0
0
0
8
8
0
8
0
8
0
0
% T
% Val:
15
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
65
% W
% Tyr:
0
0
0
0
0
8
0
65
0
8
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _