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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FXYD2 All Species: 10.91
Human Site: Y23 Identified Species: 30
UniProt: P54710 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54710 NP_001120961.1 66 7283 Y23 V D P F Y Y D Y E T V R N G G
Chimpanzee Pan troglodytes XP_001158882 61 6792 G24 D Y E T V R N G G L I F A G L
Rhesus Macaque Macaca mulatta XP_001092388 61 6764 N23 Y D Y E T V R N G G L I F A G
Dog Lupus familis XP_860824 61 6825 G24 D Y E T V R N G G L I F A A L
Cat Felis silvestris
Mouse Mus musculus Q04646 70 7501 Y27 E N P F E Y D Y E T V R K G G
Rat Rattus norvegicus Q04679 66 7239 Y23 E N P F E Y D Y E T V R K G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521655 64 7012 A23 R F H Y D Y D A V R N G G L I
Chicken Gallus gallus NP_001074348 95 10193 Y34 E D P F N Y D Y Q S L R I G G
Frog Xenopus laevis O13001 61 6981 R23 T Y D Y E T I R K G G L I F A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 86.3 72.7 N.A. 68.5 75.7 N.A. 62.1 33.6 48.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 89.3 87.8 81.8 N.A. 80 84.8 N.A. 77.2 46.3 62.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 13.3 0 N.A. 73.3 73.3 N.A. 13.3 60 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 13.3 N.A. 80 80 N.A. 20 80 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 0 0 23 23 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 23 34 12 0 12 0 56 0 0 0 0 0 0 0 0 % D
% Glu: 34 0 23 12 34 0 0 0 34 0 0 0 0 0 0 % E
% Phe: 0 12 0 45 0 0 0 0 0 0 0 23 12 12 0 % F
% Gly: 0 0 0 0 0 0 0 23 34 23 12 12 12 56 56 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 23 12 23 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 12 0 0 0 23 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 23 23 12 0 12 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 23 0 0 12 0 23 12 0 0 12 0 12 0 0 % N
% Pro: 0 0 45 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 23 12 12 0 12 0 45 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % S
% Thr: 12 0 0 23 12 12 0 0 0 34 0 0 0 0 0 % T
% Val: 12 0 0 0 23 12 0 0 12 0 34 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 34 12 23 12 56 0 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _