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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHA5 All Species: 9.09
Human Site: S4 Identified Species: 22.22
UniProt: P54756 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54756 NP_004430.4 1037 114803 S4 _ _ _ _ M R G S G P R G A G R
Chimpanzee Pan troglodytes XP_001165182 1037 114815 S4 _ _ _ _ M R G S G P R G A G R
Rhesus Macaque Macaca mulatta XP_001110034 1038 114840 S4 _ _ _ _ M R G S G P R G A G R
Dog Lupus familis XP_545052 972 108820
Cat Felis silvestris
Mouse Mus musculus P29319 983 109937
Rat Rattus norvegicus P54757 1005 110989 P6 _ _ M R G S G P R G A G R R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510807 979 108960
Chicken Gallus gallus P54755 1013 112227 R4 _ _ _ _ M G L R G G G G R A G
Frog Xenopus laevis Q91845 986 109822
Zebra Danio Brachydanio rerio O13146 981 109636
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.2 63.8 N.A. 64 92.8 N.A. 90 90.6 62.5 60.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.9 99.6 78.6 N.A. 78.6 94.1 N.A. 92.3 93.9 75.4 73.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 0 23 N.A. 0 27.2 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 0 23 N.A. 0 27.2 0 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 30 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 40 0 40 20 10 50 0 30 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 10 0 40 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 30 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 30 0 10 10 0 30 0 20 10 40 % R
% Ser: 0 0 0 0 0 10 0 30 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 50 50 40 40 0 0 0 0 0 0 0 0 0 0 0 % _