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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGLU
All Species:
24.24
Human Site:
S325
Identified Species:
44.44
UniProt:
P54802
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54802
NP_000254.2
743
82167
S325
Q
P
P
S
S
E
P
S
Y
L
A
A
A
T
T
Chimpanzee
Pan troglodytes
XP_523654
743
82219
S325
Q
P
P
S
S
E
P
S
Y
L
A
A
A
T
T
Rhesus Macaque
Macaca mulatta
XP_001095618
704
77136
A325
S
S
A
P
S
Y
L
A
A
A
T
T
A
V
Y
Dog
Lupus familis
XP_548088
747
82985
S326
Q
P
P
S
S
E
P
S
Y
L
A
S
A
T
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_038820
739
82578
S323
Q
P
P
F
S
D
P
S
Y
L
A
A
T
T
A
Rat
Rattus norvegicus
XP_001081442
739
82393
S323
Q
P
P
F
S
D
P
S
Y
L
A
A
A
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234488
602
68769
R255
P
Q
V
Q
A
V
L
R
A
V
P
L
G
R
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688608
757
86762
T335
P
P
A
S
S
D
P
T
Y
L
A
S
I
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652045
778
89728
E344
E
P
P
V
A
K
P
E
Y
M
R
S
T
A
A
Honey Bee
Apis mellifera
XP_623833
1139
132435
K706
E
P
Y
T
S
E
L
K
F
L
R
N
I
G
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785272
767
87420
S336
N
K
P
K
S
R
D
S
A
Y
L
S
A
A
S
Poplar Tree
Populus trichocarpa
XP_002314048
806
91892
S354
N
E
N
S
P
P
T
S
D
P
A
Y
I
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196873
806
92671
S352
N
E
N
T
P
P
T
S
E
P
E
Y
I
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86
85.2
N.A.
82.2
81.1
N.A.
N.A.
53.1
N.A.
56.2
N.A.
39.8
31.2
N.A.
41.3
Protein Similarity:
100
99.7
87.6
91.6
N.A.
89.5
90
N.A.
N.A.
64.8
N.A.
73.1
N.A.
55
42.8
N.A.
58.6
P-Site Identity:
100
100
13.3
86.6
N.A.
73.3
80
N.A.
N.A.
0
N.A.
46.6
N.A.
26.6
26.6
N.A.
26.6
P-Site Similarity:
100
100
20
93.3
N.A.
80
86.6
N.A.
N.A.
13.3
N.A.
73.3
N.A.
60
46.6
N.A.
40
Percent
Protein Identity:
38.8
N.A.
N.A.
37.3
N.A.
N.A.
Protein Similarity:
58.8
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
16
0
0
8
24
8
54
31
47
16
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
24
8
0
8
0
0
0
0
0
0
% D
% Glu:
16
16
0
0
0
31
0
8
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% I
% Lys:
0
8
0
8
0
8
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
24
0
0
54
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
24
0
16
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
16
62
54
8
16
16
54
0
0
16
8
0
0
0
0
% P
% Gln:
39
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
16
0
0
8
8
% R
% Ser:
8
8
0
39
70
0
0
62
0
0
0
31
0
24
24
% S
% Thr:
0
0
0
16
0
0
16
8
0
0
8
8
16
39
16
% T
% Val:
0
0
8
8
0
8
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
54
8
0
16
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _