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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAGLU All Species: 25.15
Human Site: S387 Identified Species: 46.11
UniProt: P54802 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54802 NP_000254.2 743 82167 S387 V L D L F A E S Q P V Y T R T
Chimpanzee Pan troglodytes XP_523654 743 82219 S387 V L D L F A E S Q P V Y T R T
Rhesus Macaque Macaca mulatta XP_001095618 704 77136 S384 V L D L F A E S Q P V Y T L T
Dog Lupus familis XP_548088 747 82985 S388 V L D L F A E S Q P V Y I Q T
Cat Felis silvestris
Mouse Mus musculus NP_038820 739 82578 S385 V L D L F A E S H P V Y M H T
Rat Rattus norvegicus XP_001081442 739 82393 T385 V L D L F A E T Q P V Y S R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234488 602 68769 W288 F Y G Q P F I W C M L H N F G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688608 757 86762 S397 V L D L F A E S M P V Y S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_652045 778 89728 Q405 V L D L Q S E Q F P Q Y E L T
Honey Bee Apis mellifera XP_623833 1139 132435 Q768 V L D L Q S E Q F P Q Y K R L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785272 767 87420 A398 V L D L Y A E A R P F Y K T T
Poplar Tree Populus trichocarpa XP_002314048 806 91892 A419 V L D L F A E A K P I W K N S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196873 806 92671 V417 V L D L Y A E V K P I W N K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 86 85.2 N.A. 82.2 81.1 N.A. N.A. 53.1 N.A. 56.2 N.A. 39.8 31.2 N.A. 41.3
Protein Similarity: 100 99.7 87.6 91.6 N.A. 89.5 90 N.A. N.A. 64.8 N.A. 73.1 N.A. 55 42.8 N.A. 58.6
P-Site Identity: 100 100 93.3 86.6 N.A. 80 86.6 N.A. N.A. 0 N.A. 80 N.A. 53.3 53.3 N.A. 60
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 100 N.A. N.A. 13.3 N.A. 86.6 N.A. 60 60 N.A. 80
Percent
Protein Identity: 38.8 N.A. N.A. 37.3 N.A. N.A.
Protein Similarity: 58.8 N.A. N.A. 58.9 N.A. N.A.
P-Site Identity: 53.3 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 86.6 N.A. N.A. 86.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 77 0 16 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 93 0 0 0 0 0 8 0 0 % E
% Phe: 8 0 0 0 62 8 0 0 16 0 8 0 0 8 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 8 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 16 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 16 0 0 0 24 8 0 % K
% Leu: 0 93 0 93 0 0 0 0 0 0 8 0 0 16 8 % L
% Met: 0 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 16 8 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 93 0 0 0 0 0 % P
% Gln: 0 0 0 8 16 0 0 16 39 0 16 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 31 0 % R
% Ser: 0 0 0 0 0 16 0 47 0 0 0 0 16 8 16 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 24 8 70 % T
% Val: 93 0 0 0 0 0 0 8 0 0 54 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 16 0 0 0 % W
% Tyr: 0 8 0 0 16 0 0 0 0 0 0 77 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _