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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGLU
All Species:
7.27
Human Site:
S456
Identified Species:
13.33
UniProt:
P54802
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54802
NP_000254.2
743
82167
S456
S
Q
N
E
V
V
Y
S
L
M
A
E
L
G
W
Chimpanzee
Pan troglodytes
XP_523654
743
82219
S456
S
Q
N
E
V
V
Y
S
L
M
A
E
L
G
W
Rhesus Macaque
Macaca mulatta
XP_001095618
704
77136
P431
P
E
A
A
R
L
F
P
N
S
T
M
V
G
T
Dog
Lupus familis
XP_548088
747
82985
A457
G
Q
N
E
V
V
Y
A
L
M
A
E
L
G
W
Cat
Felis silvestris
Mouse
Mus musculus
NP_038820
739
82578
A454
G
Q
N
E
V
V
Y
A
L
M
A
E
L
G
W
Rat
Rattus norvegicus
XP_001081442
739
82393
A454
G
Q
N
E
V
V
Y
A
L
M
A
E
L
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234488
602
68769
I332
T
G
L
V
P
E
G
I
E
Q
N
D
M
V
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688608
757
86762
E466
E
Q
N
P
V
I
Y
E
L
M
S
E
L
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652045
778
89728
S474
G
Q
N
Y
V
M
Y
S
F
T
L
E
R
G
W
Honey Bee
Apis mellifera
XP_623833
1139
132435
E837
N
Q
N
Y
V
I
Y
E
L
M
N
E
M
A
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785272
767
87420
N467
F
Q
N
Y
V
M
Y
N
F
L
T
D
M
T
W
Poplar Tree
Populus trichocarpa
XP_002314048
806
91892
E488
E
H
N
P
V
V
Y
E
L
M
S
E
M
A
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196873
806
92671
E486
E
Q
N
P
V
V
Y
E
L
T
S
E
M
A
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86
85.2
N.A.
82.2
81.1
N.A.
N.A.
53.1
N.A.
56.2
N.A.
39.8
31.2
N.A.
41.3
Protein Similarity:
100
99.7
87.6
91.6
N.A.
89.5
90
N.A.
N.A.
64.8
N.A.
73.1
N.A.
55
42.8
N.A.
58.6
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
60
N.A.
53.3
46.6
N.A.
33.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
N.A.
73.3
N.A.
60
73.3
N.A.
66.6
Percent
Protein Identity:
38.8
N.A.
N.A.
37.3
N.A.
N.A.
Protein Similarity:
58.8
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
24
0
0
39
0
0
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% D
% Glu:
24
8
0
39
0
8
0
31
8
0
0
77
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
16
0
0
0
0
0
16
% F
% Gly:
31
8
0
0
0
0
8
0
0
0
0
0
0
54
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
8
0
0
70
8
8
0
47
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
62
0
8
39
0
0
% M
% Asn:
8
0
85
0
0
0
0
8
8
0
16
0
0
0
0
% N
% Pro:
8
0
0
24
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
77
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
16
0
0
0
0
0
0
24
0
8
24
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
16
16
0
0
8
8
% T
% Val:
0
0
0
8
85
54
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% W
% Tyr:
0
0
0
24
0
0
85
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _