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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGLU
All Species:
22.42
Human Site:
S500
Identified Species:
41.11
UniProt:
P54802
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54802
NP_000254.2
743
82167
S500
A
W
R
L
L
L
R
S
V
Y
N
C
S
G
E
Chimpanzee
Pan troglodytes
XP_523654
743
82219
S500
A
W
R
L
L
L
R
S
V
Y
N
C
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001095618
704
77136
A470
D
P
V
P
D
L
A
A
W
V
T
N
F
A
A
Dog
Lupus familis
XP_548088
747
82985
S501
A
W
R
L
L
L
R
S
V
Y
N
C
S
G
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_038820
739
82578
S498
A
W
K
L
L
L
R
S
V
Y
N
C
S
G
E
Rat
Rattus norvegicus
XP_001081442
739
82393
S498
A
W
R
L
L
L
R
S
V
Y
N
C
S
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234488
602
68769
A371
R
R
Y
G
A
P
D
A
A
A
G
A
A
W
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688608
757
86762
S509
A
W
Q
L
L
F
R
S
V
Y
N
C
T
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652045
778
89728
Y519
L
L
L
K
N
S
V
Y
S
F
R
G
L
Q
K
Honey Bee
Apis mellifera
XP_623833
1139
132435
K880
V
T
A
W
K
G
F
K
N
T
V
Y
N
F
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785272
767
87420
E512
E
A
W
V
I
L
K
E
T
V
Y
N
N
T
G
Poplar Tree
Populus trichocarpa
XP_002314048
806
91892
Q566
S
G
S
N
I
S
E
Q
D
N
M
R
I
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196873
806
92671
D565
Q
D
D
L
K
Q
K
D
S
Y
M
I
S
T
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86
85.2
N.A.
82.2
81.1
N.A.
N.A.
53.1
N.A.
56.2
N.A.
39.8
31.2
N.A.
41.3
Protein Similarity:
100
99.7
87.6
91.6
N.A.
89.5
90
N.A.
N.A.
64.8
N.A.
73.1
N.A.
55
42.8
N.A.
58.6
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
N.A.
0
N.A.
66.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
20
N.A.
80
N.A.
13.3
6.6
N.A.
33.3
Percent
Protein Identity:
38.8
N.A.
N.A.
37.3
N.A.
N.A.
Protein Similarity:
58.8
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
8
8
0
8
0
8
16
8
8
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% C
% Asp:
8
8
8
0
8
0
8
8
8
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
39
% E
% Phe:
0
0
0
0
0
8
8
0
0
8
0
0
8
8
0
% F
% Gly:
0
8
0
8
0
8
0
0
0
0
8
8
0
39
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
0
8
8
16
0
16
8
0
0
0
0
0
0
8
% K
% Leu:
8
8
8
54
47
54
0
0
0
0
0
0
8
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
8
8
47
16
16
0
0
% N
% Pro:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
8
0
0
8
0
8
0
0
0
0
0
8
8
% Q
% Arg:
8
8
31
0
0
0
47
0
0
0
8
8
0
0
0
% R
% Ser:
8
0
8
0
0
16
0
47
16
0
0
0
47
0
8
% S
% Thr:
0
8
0
0
0
0
0
0
8
8
8
0
8
16
0
% T
% Val:
8
0
8
8
0
0
8
0
47
16
8
0
0
0
0
% V
% Trp:
0
47
8
8
0
0
0
0
8
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
54
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _