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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGLU
All Species:
23.03
Human Site:
S581
Identified Species:
42.22
UniProt:
P54802
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54802
NP_000254.2
743
82167
S581
L
Y
Y
E
E
A
R
S
A
Y
L
S
K
E
L
Chimpanzee
Pan troglodytes
XP_523654
743
82219
S581
L
Y
Y
E
E
A
R
S
A
Y
L
S
K
E
L
Rhesus Macaque
Macaca mulatta
XP_001095618
704
77136
P551
A
P
S
L
A
A
S
P
A
F
R
Y
D
L
L
Dog
Lupus familis
XP_548088
747
82985
S582
L
Y
Y
V
E
A
R
S
A
Y
L
R
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_038820
739
82578
T579
L
C
Y
E
E
A
R
T
A
Y
L
K
Q
E
L
Rat
Rattus norvegicus
XP_001081442
739
82393
T579
S
C
Y
E
E
A
R
T
A
F
L
N
Q
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234488
602
68769
Q452
V
T
R
Q
A
V
Q
Q
L
V
A
D
Y
Y
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688608
757
86762
S590
E
F
Y
K
D
I
K
S
A
F
Q
T
Q
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652045
778
89728
R600
D
Q
L
Y
I
N
L
R
S
A
Y
R
K
R
Q
Honey Bee
Apis mellifera
XP_623833
1139
132435
I961
D
E
I
Y
T
D
L
I
E
S
F
N
K
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785272
767
87420
V593
D
F
Q
Q
K
L
M
V
S
F
R
I
R
N
A
Poplar Tree
Populus trichocarpa
XP_002314048
806
91892
I647
Q
V
Y
R
D
A
M
I
A
F
R
R
K
D
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196873
806
92671
T646
Q
V
Y
T
E
A
V
T
A
F
V
K
K
D
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86
85.2
N.A.
82.2
81.1
N.A.
N.A.
53.1
N.A.
56.2
N.A.
39.8
31.2
N.A.
41.3
Protein Similarity:
100
99.7
87.6
91.6
N.A.
89.5
90
N.A.
N.A.
64.8
N.A.
73.1
N.A.
55
42.8
N.A.
58.6
P-Site Identity:
100
100
20
86.6
N.A.
73.3
53.3
N.A.
N.A.
0
N.A.
26.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
26.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
20
N.A.
80
N.A.
13.3
20
N.A.
40
Percent
Protein Identity:
38.8
N.A.
N.A.
37.3
N.A.
N.A.
Protein Similarity:
58.8
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
62
0
0
70
8
8
0
0
0
16
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
0
0
16
8
0
0
0
0
0
8
8
24
0
% D
% Glu:
8
8
0
31
47
0
0
0
8
0
0
0
0
31
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
47
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
16
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
8
0
8
0
0
0
0
16
54
16
0
% K
% Leu:
31
0
8
8
0
8
16
0
8
0
39
0
0
8
54
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
16
0
8
8
% N
% Pro:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
16
8
8
16
0
0
8
8
0
0
8
0
24
0
16
% Q
% Arg:
0
0
8
8
0
0
39
8
0
0
24
24
8
8
0
% R
% Ser:
8
0
8
0
0
0
8
31
16
8
0
16
0
0
0
% S
% Thr:
0
8
0
8
8
0
0
24
0
0
0
8
0
0
0
% T
% Val:
8
16
0
8
0
8
8
8
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
62
16
0
0
0
0
0
31
8
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _