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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGLU
All Species:
12.12
Human Site:
S620
Identified Species:
22.22
UniProt:
P54802
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54802
NP_000254.2
743
82167
S620
D
S
R
F
L
L
G
S
W
L
E
Q
A
R
A
Chimpanzee
Pan troglodytes
XP_523654
743
82219
S620
D
S
R
F
L
L
G
S
W
L
E
Q
A
R
A
Rhesus Macaque
Macaca mulatta
XP_001095618
704
77136
R590
K
E
L
T
S
L
L
R
A
G
G
V
L
A
Y
Dog
Lupus familis
XP_548088
747
82985
R621
D
S
R
F
L
L
G
R
W
L
E
Q
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_038820
739
82578
T618
S
S
H
F
L
L
G
T
W
L
D
Q
A
R
K
Rat
Rattus norvegicus
XP_001081442
739
82393
T618
N
S
H
F
L
L
G
T
W
L
D
Q
A
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234488
602
68769
L491
L
L
P
E
L
D
A
L
L
G
S
Q
R
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688608
757
86762
A629
N
E
H
F
L
L
G
A
W
L
Q
Q
A
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652045
778
89728
N639
S
R
N
F
L
L
G
N
W
L
Q
Q
A
K
Q
Honey Bee
Apis mellifera
XP_623833
1139
132435
K1000
S
E
D
F
L
L
G
K
W
L
K
M
A
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785272
767
87420
W632
E
D
W
L
L
G
T
W
L
E
D
A
K
S
L
Poplar Tree
Populus trichocarpa
XP_002314048
806
91892
W686
D
N
F
L
L
G
T
W
L
E
S
A
K
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196873
806
92671
W685
D
N
C
L
L
G
T
W
L
E
S
A
K
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86
85.2
N.A.
82.2
81.1
N.A.
N.A.
53.1
N.A.
56.2
N.A.
39.8
31.2
N.A.
41.3
Protein Similarity:
100
99.7
87.6
91.6
N.A.
89.5
90
N.A.
N.A.
64.8
N.A.
73.1
N.A.
55
42.8
N.A.
58.6
P-Site Identity:
100
100
6.6
93.3
N.A.
66.6
66.6
N.A.
N.A.
13.3
N.A.
53.3
N.A.
53.3
46.6
N.A.
6.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
80
86.6
N.A.
N.A.
13.3
N.A.
86.6
N.A.
73.3
60
N.A.
20
Percent
Protein Identity:
38.8
N.A.
N.A.
37.3
N.A.
N.A.
Protein Similarity:
58.8
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
8
0
0
24
62
8
24
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
8
8
0
0
8
0
0
0
0
24
0
0
0
8
% D
% Glu:
8
24
0
8
0
0
0
0
0
24
24
0
0
0
8
% E
% Phe:
0
0
8
62
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
24
62
0
0
16
8
0
0
0
0
% G
% His:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
0
0
8
0
24
31
8
% K
% Leu:
8
8
8
24
93
70
8
8
31
62
0
0
8
8
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
16
8
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
62
0
8
8
% Q
% Arg:
0
8
24
0
0
0
0
16
0
0
0
0
8
39
0
% R
% Ser:
24
39
0
0
8
0
0
16
0
0
24
0
0
8
8
% S
% Thr:
0
0
0
8
0
0
24
16
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
24
62
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _