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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGLU
All Species:
28.18
Human Site:
T125
Identified Species:
51.67
UniProt:
P54802
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54802
NP_000254.2
743
82167
T125
P
G
E
L
T
E
A
T
P
N
R
Y
R
Y
Y
Chimpanzee
Pan troglodytes
XP_523654
743
82219
T125
P
G
E
L
T
E
A
T
P
N
R
Y
R
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001095618
704
77136
T125
P
G
E
L
T
E
A
T
P
N
R
Y
R
Y
Y
Dog
Lupus familis
XP_548088
747
82985
T126
P
Q
V
L
T
E
A
T
P
N
R
Y
R
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_038820
739
82578
T123
P
D
G
L
T
E
T
T
P
N
R
Y
R
Y
Y
Rat
Rattus norvegicus
XP_001081442
739
82393
T123
P
D
G
L
T
E
A
T
P
N
R
Y
R
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234488
602
68769
W68
Y
S
Y
V
W
W
G
W
E
R
W
E
R
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688608
757
86762
T135
T
G
V
L
R
I
S
T
P
H
R
F
R
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652045
778
89728
S145
N
V
T
I
E
S
K
S
A
S
P
I
I
Y
H
Honey Bee
Apis mellifera
XP_623833
1139
132435
D508
R
V
K
I
S
S
N
D
R
F
R
Y
Y
Q
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785272
767
87420
S136
H
P
P
L
K
V
T
S
P
N
R
F
R
F
Y
Poplar Tree
Populus trichocarpa
XP_002314048
806
91892
R154
D
K
G
V
M
I
Q
R
P
V
P
W
N
Y
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196873
806
92671
R152
S
K
R
I
F
I
R
R
P
V
P
W
N
Y
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86
85.2
N.A.
82.2
81.1
N.A.
N.A.
53.1
N.A.
56.2
N.A.
39.8
31.2
N.A.
41.3
Protein Similarity:
100
99.7
87.6
91.6
N.A.
89.5
90
N.A.
N.A.
64.8
N.A.
73.1
N.A.
55
42.8
N.A.
58.6
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
N.A.
6.6
N.A.
53.3
N.A.
6.6
13.3
N.A.
40
P-Site Similarity:
100
100
100
86.6
N.A.
80
86.6
N.A.
N.A.
13.3
N.A.
73.3
N.A.
33.3
33.3
N.A.
60
Percent
Protein Identity:
38.8
N.A.
N.A.
37.3
N.A.
N.A.
Protein Similarity:
58.8
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
39
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
24
0
8
47
0
0
8
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
0
16
0
8
0
% F
% Gly:
0
31
24
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
24
0
24
0
0
0
0
0
8
8
0
8
% I
% Lys:
0
16
8
0
8
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
54
0
0
16
0
8
% N
% Pro:
47
8
8
0
0
0
0
0
77
0
24
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
8
0
8
0
8
16
8
8
70
0
70
0
0
% R
% Ser:
8
8
0
0
8
16
8
16
0
8
0
0
0
0
0
% S
% Thr:
8
0
8
0
47
0
16
54
0
0
0
0
0
0
0
% T
% Val:
0
16
16
16
0
8
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
8
0
8
0
0
8
16
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
0
0
0
0
54
8
77
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _