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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GALC
All Species:
11.82
Human Site:
S453
Identified Species:
28.89
UniProt:
P54803
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54803
NP_000144.2
685
77033
S453
W
L
L
D
S
D
G
S
F
T
L
S
L
H
E
Chimpanzee
Pan troglodytes
XP_001136375
685
76923
S453
W
L
L
D
S
D
G
S
F
T
L
S
L
H
E
Rhesus Macaque
Macaca mulatta
O02791
685
77072
S453
W
L
L
D
S
N
G
S
F
T
L
K
L
Q
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P54818
684
77238
S453
W
L
L
D
G
S
G
S
F
T
L
E
L
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511899
404
45786
Q177
R
D
G
L
M
T
A
Q
E
P
W
S
G
H
Y
Chicken
Gallus gallus
XP_421304
673
75867
L445
V
W
R
G
S
F
A
L
D
L
D
V
D
E
V
Frog
Xenopus laevis
Q498K0
677
75042
F444
V
K
V
Q
N
G
S
F
T
L
Q
L
G
V
N
Zebra Danio
Brachydanio rerio
Q5SNX7
660
73802
K433
H
N
G
L
L
S
L
K
L
D
V
D
E
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95QT2
556
63541
L329
N
S
T
I
T
I
L
L
P
V
N
S
F
G
I
Sea Urchin
Strong. purpuratus
XP_789829
590
64748
K363
Y
V
S
L
T
D
G
K
N
F
T
I
V
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
N.A.
N.A.
82.7
N.A.
N.A.
42.3
67.7
64.2
62
N.A.
N.A.
N.A.
22.4
46.7
Protein Similarity:
100
99.5
97.8
N.A.
N.A.
89.9
N.A.
N.A.
49.9
78.6
77.5
76
N.A.
N.A.
N.A.
38.3
61
P-Site Identity:
100
100
80
N.A.
N.A.
73.3
N.A.
N.A.
13.3
6.6
0
0
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
100
86.6
N.A.
N.A.
73.3
N.A.
N.A.
13.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
40
0
30
0
0
10
10
10
10
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
10
20
50
% E
% Phe:
0
0
0
0
0
10
0
10
40
10
0
0
10
0
10
% F
% Gly:
0
0
20
10
10
10
50
0
0
0
0
0
20
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
0
10
0
10
10
% I
% Lys:
0
10
0
0
0
0
0
20
0
0
0
10
0
0
0
% K
% Leu:
0
40
40
30
10
0
20
20
10
20
40
10
40
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
10
10
0
0
10
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
10
0
0
10
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
40
20
10
40
0
0
0
40
0
0
0
% S
% Thr:
0
0
10
0
20
10
0
0
10
40
10
0
0
0
0
% T
% Val:
20
10
10
0
0
0
0
0
0
10
10
10
10
20
10
% V
% Trp:
40
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _