Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AK2 All Species: 0.61
Human Site: Y12 Identified Species: 1.11
UniProt: P54819 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54819 NP_001616.1 239 26478 Y12 V P A A E P E Y P K G I R A V
Chimpanzee Pan troglodytes XP_001165055 197 22071
Rhesus Macaque Macaca mulatta XP_001105613 202 22247
Dog Lupus familis XP_535321 241 26551 P12 V P A A E P A P E S P K G I R
Cat Felis silvestris
Mouse Mus musculus Q9WTP6 239 26450 I12 V L A S E P E I P K G I R A V
Rat Rattus norvegicus P29410 239 26361 H12 A L A P E P E H P E G I R A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508642 232 25832 Q13 Q L L L E G T Q D A E L H L D
Chicken Gallus gallus XP_425786 240 26137 L19 G Q A P G T G L R R G I R A V
Frog Xenopus laevis Q8AVD3 241 26508 M14 A P A E R G S M M E G I R A I
Zebra Danio Brachydanio rerio Q1L8L9 241 26598 I14 E D D T V S G I R K G I R A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U915 240 26524 Y12 A A V P V E R Y E P E N I G I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34346 251 27907 L23 S A G P T E T L A R G I R A I
Sea Urchin Strong. purpuratus XP_001178566 243 26511 L14 P K P Q F D D L P D G I K A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.4 79 94.6 N.A. 94.9 92.8 N.A. 80.7 80.4 79.2 78 N.A. 63.3 N.A. 60.1 68.3
Protein Similarity: 100 82.4 81.5 97.5 N.A. 97.4 96.6 N.A. 88.2 89.1 89.6 87.9 N.A. 77.9 N.A. 73.7 81.8
P-Site Identity: 100 0 0 40 N.A. 80 66.6 N.A. 6.6 40 40 33.3 N.A. 6.6 N.A. 26.6 26.6
P-Site Similarity: 100 0 0 40 N.A. 86.6 80 N.A. 13.3 46.6 53.3 40 N.A. 13.3 N.A. 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 16 47 16 0 0 8 0 8 8 0 0 0 62 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 8 8 0 8 8 0 0 0 0 8 % D
% Glu: 8 0 0 8 39 16 24 0 16 16 16 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 8 16 16 0 0 0 62 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 16 0 0 0 62 8 8 39 % I
% Lys: 0 8 0 0 0 0 0 0 0 24 0 8 8 0 0 % K
% Leu: 0 24 8 8 0 0 0 24 0 0 0 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 24 8 31 0 31 0 8 31 8 8 0 0 0 0 % P
% Gln: 8 8 0 8 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 8 0 16 16 0 0 54 0 8 % R
% Ser: 8 0 0 8 0 8 8 0 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 8 8 8 16 0 0 0 0 0 0 0 0 % T
% Val: 24 0 8 0 16 0 0 0 0 0 0 0 0 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _