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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRRX1 All Species: 10.3
Human Site: S67 Identified Species: 25.19
UniProt: P54821 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54821 NP_008833.1 245 27296 S67 A G R S L L E S P G L T S G S
Chimpanzee Pan troglodytes A2T711 184 20085 A22 G L G P G E E A P K K K H R R
Rhesus Macaque Macaca mulatta XP_001097189 200 22539 H38 K K N F S V S H L L D L E E A
Dog Lupus familis XP_548419 212 23753 P49 Q P H S G E C P S P G R G G A
Cat Felis silvestris
Mouse Mus musculus Q06348 247 26408 G71 G A A R E P S G G S S G T E A
Rat Rattus norvegicus P63014 245 27251 S67 A G R S L L E S P G L T S G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514860 202 23193 D39 W E N A D V D D Q L N S E E K
Chicken Gallus gallus Q05437 245 27183 S67 P G R S L L E S P G L T S G S
Frog Xenopus laevis O42567 325 36295 S103 P Y S A K T S S E C L S P G L
Zebra Danio Brachydanio rerio O42358 292 32739 R79 K H F D G V C R S T V M V S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31 81.6 53 N.A. 59.1 99.5 N.A. 71.8 91.4 31.6 27.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.4 81.6 64.4 N.A. 68.4 100 N.A. 75.5 92.6 48 45.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 0 13.3 N.A. 0 100 N.A. 0 93.3 20 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 13.3 20 N.A. 13.3 100 N.A. 26.6 93.3 33.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 10 20 0 0 0 10 0 0 0 0 0 0 30 % A
% Cys: 0 0 0 0 0 0 20 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 10 10 0 0 10 0 0 0 0 % D
% Glu: 0 10 0 0 10 20 40 0 10 0 0 0 20 30 0 % E
% Phe: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 30 10 0 30 0 0 10 10 30 10 10 10 50 0 % G
% His: 0 10 10 0 0 0 0 10 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 20 10 0 0 10 0 0 0 0 10 10 10 0 0 10 % K
% Leu: 0 10 0 0 30 30 0 0 10 20 40 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 20 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 20 10 0 10 0 10 0 10 40 10 0 0 10 0 10 % P
% Gln: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 30 10 0 0 0 10 0 0 0 10 0 10 10 % R
% Ser: 0 0 10 40 10 0 30 40 20 10 10 20 30 10 30 % S
% Thr: 0 0 0 0 0 10 0 0 0 10 0 30 10 0 0 % T
% Val: 0 0 0 0 0 30 0 0 0 0 10 0 10 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _