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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRL All Species: 23.03
Human Site: T52 Identified Species: 50.67
UniProt: P54845 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54845 NP_006168.1 237 25940 T52 S S V P P S P T F S E P G M V
Chimpanzee Pan troglodytes XP_525325 233 25698 P56 P H P H H A Y P G A G V A H D
Rhesus Macaque Macaca mulatta XP_001111563 239 26122 T52 S S V P P S P T F S E P G M V
Dog Lupus familis XP_547742 237 25906 T52 S S V P P S P T F S E P G M A
Cat Felis silvestris
Mouse Mus musculus P54846 237 26065 T52 S S V P P S P T F S E P G M V
Rat Rattus norvegicus P54844 369 38439 S72 S S V P P S P S F S A P S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518092 97 11214
Chicken Gallus gallus O42290 286 32427 S67 S S V P S S P S F C A P S P G
Frog Xenopus laevis Q6DE84 313 35730 S66 T P I S T P C S S V P S S P S
Zebra Danio Brachydanio rerio A3KMR8 315 35689 S67 S S V P S S P S F C A P S P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42774 315 33914 A80 G T P V P Y P A M Y P P G A V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.9 97 93.6 N.A. 89.4 37.9 N.A. 34.5 47.2 40.5 42.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 48 98.7 95.7 N.A. 92.4 46.8 N.A. 37.5 58.7 54.3 55.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 93.3 N.A. 100 66.6 N.A. 0 53.3 0 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 93.3 N.A. 100 73.3 N.A. 0 60 20 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 10 28 0 10 10 19 % A
% Cys: 0 0 0 0 0 0 10 0 0 19 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 0 10 0 46 0 19 % G
% His: 0 10 0 10 10 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 37 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 19 64 55 10 73 10 0 0 19 73 0 37 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 64 64 0 10 19 64 0 37 10 46 0 10 37 0 10 % S
% Thr: 10 10 0 0 10 0 0 37 0 0 0 0 0 0 0 % T
% Val: 0 0 64 10 0 0 0 0 0 10 0 10 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _