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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EMP2 All Species: 28.48
Human Site: S142 Identified Species: 69.63
UniProt: P54851 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54851 NP_001415.1 167 19199 S142 R E G S Y G Y S Y I L A W V A
Chimpanzee Pan troglodytes A5A6N6 167 19216 S142 R E G S Y G Y S Y I L A W V A
Rhesus Macaque Macaca mulatta XP_001103125 167 19237 S142 E G G S Y G Y S Y I L A W V A
Dog Lupus familis XP_547130 167 19138 S142 L E G S Y G Y S F I L A W V A
Cat Felis silvestris
Mouse Mus musculus O88662 172 19729 S147 Q E G S Y G Y S F I L A W V A
Rat Rattus norvegicus P25094 160 17928 A135 N D Y S Y G F A Y I L A W V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505583 167 19166 S142 D G G K Y G Y S F I L A W I A
Chicken Gallus gallus XP_414935 167 18958 S142 S K G Q Y G Y S F V L A W I A
Frog Xenopus laevis NP_001079581 165 18785 S140 D A G R F G Y S F V I A W I A
Zebra Danio Brachydanio rerio NP_001004119 153 17125 K129 T F N G Q E F K N A E Y G Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 94 85 N.A. 74.4 43.7 N.A. 77.2 70.6 62.2 55.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 97.5 92.2 N.A. 87.2 62.2 N.A. 88.6 84.4 74.2 68.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 86.6 N.A. 86.6 66.6 N.A. 66.6 60 46.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 93.3 N.A. 100 86.6 N.A. 80 86.6 80 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 0 10 0 90 0 0 90 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 40 0 0 0 10 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 10 0 0 10 0 20 0 50 0 0 0 0 0 0 % F
% Gly: 0 20 80 10 0 90 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 70 10 0 0 30 0 % I
% Lys: 0 10 0 10 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 60 0 0 0 80 0 0 0 0 0 0 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 20 0 0 0 60 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 90 0 0 % W
% Tyr: 0 0 10 0 80 0 80 0 40 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _