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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5
All Species:
63.33
Human Site:
Y14
Identified Species:
87.08
UniProt:
P55010
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55010
NP_001960.2
431
49223
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Chimpanzee
Pan troglodytes
XP_001135628
431
49234
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Rhesus Macaque
Macaca mulatta
XP_001086107
510
58170
H24
G
T
L
R
P
L
F
H
G
D
N
G
A
G
T
Dog
Lupus familis
XP_854659
425
48689
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P59325
429
48950
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Rat
Rattus norvegicus
Q07205
429
48936
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507766
428
48873
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Chicken
Gallus gallus
NP_001006488
430
49060
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Frog
Xenopus laevis
NP_001080311
434
49605
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Zebra Danio
Brachydanio rerio
NP_955885
429
49090
Y14
R
S
V
S
D
Q
F
Y
R
Y
K
M
P
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXK6
464
51681
Y15
R
S
V
T
D
I
F
Y
R
Y
K
M
P
R
L
Honey Bee
Apis mellifera
XP_392511
454
50921
Y15
R
N
V
S
D
A
F
Y
R
Y
K
M
P
R
I
Nematode Worm
Caenorhab. elegans
Q22918
436
48768
Y14
R
A
V
A
D
P
F
Y
R
Y
K
M
P
K
L
Sea Urchin
Strong. purpuratus
XP_787853
423
47400
Y14
R
A
V
T
D
Q
F
Y
R
Y
K
M
P
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P55876
451
48894
Y16
S
N
R
D
D
A
F
Y
R
Y
K
M
P
R
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8F1
439
48604
Y16
S
N
R
D
D
A
F
Y
R
Y
K
M
P
R
M
Baker's Yeast
Sacchar. cerevisiae
P38431
405
45243
Y14
R
D
N
H
D
P
F
Y
R
Y
K
M
P
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
75.8
93
N.A.
97.2
96.9
N.A.
94.9
92.8
83.4
76
N.A.
50.2
53.2
49.3
52.4
Protein Similarity:
100
99.7
80.1
95.1
N.A.
98.3
98.3
N.A.
97.6
96.7
91.9
89.5
N.A.
68
70.9
65.3
71.2
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
80
73.3
86.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
93.3
93.3
100
Percent
Protein Identity:
N.A.
30.3
N.A.
28.7
35.2
N.A.
Protein Similarity:
N.A.
46.7
N.A.
47.3
53.1
N.A.
P-Site Identity:
N.A.
60
N.A.
60
60
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
6
0
18
0
0
0
0
0
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
12
95
0
0
0
0
6
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% F
% Gly:
6
0
0
0
0
0
0
0
6
0
0
6
0
6
0
% G
% His:
0
0
0
6
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
95
0
0
6
0
% K
% Leu:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
71
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
95
0
0
12
% M
% Asn:
0
18
6
0
0
0
0
0
0
0
6
0
0
0
0
% N
% Pro:
0
0
0
0
6
12
0
0
0
0
0
0
95
6
0
% P
% Gln:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% Q
% Arg:
83
0
12
6
0
0
0
0
95
0
0
0
0
83
0
% R
% Ser:
12
59
0
59
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
6
0
12
0
0
0
0
0
0
0
0
0
0
6
% T
% Val:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
95
0
95
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _